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Ovarian failure following abdominal irradiation in childhood.

dc.contributor.authorShalet, Stephen M
dc.contributor.authorBeardwell, Colin G
dc.contributor.authorJones, P H
dc.contributor.authorPearson, D
dc.contributor.authorOrrell, D
dc.date.accessioned2011-06-23T17:17:00Z
dc.date.available2011-06-23T17:17:00Z
dc.date.issued1976-06
dc.identifier.citationOvarian failure following abdominal irradiation in childhood. 1976, 33 (6):655-8 Br J Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid938613
dc.identifier.urihttp://hdl.handle.net/10541/134319
dc.description.abstractOvarian function was studied in 18 female patients treated for abdominal tumours during childhood. All received abdominal radiotherapy as part of their treatment and were studied between 1 and 26 years after irradiation. The serum gonadotrophins and oestradiol levels were consistent with ovarian failure in each case but there was a disproportionate elevation in serum follicle stimulating hormone (FSH) when compared to serum luteinizing hormone (LH) in 16. In 2 patients, the radiotherapeutic field extended downwards only as far as the sacral promontory. However, these 2 girls show similar evidence of ovarian failure to that in the other 16.
dc.language.isoenen
dc.subjectAbdominal Canceren
dc.subject.meshAbdominal Neoplasms
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshEstradiol
dc.subject.meshFemale
dc.subject.meshFollicle Stimulating Hormone
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshLuteinizing Hormone
dc.subject.meshMenstruation
dc.subject.meshOvary
dc.subject.meshRadiotherapy
dc.titleOvarian failure following abdominal irradiation in childhood.en
dc.typeArticleen
dc.identifier.journalBritish Journal of Canceren
dc.identifier.pmcidPMC2025110
html.description.abstractOvarian function was studied in 18 female patients treated for abdominal tumours during childhood. All received abdominal radiotherapy as part of their treatment and were studied between 1 and 26 years after irradiation. The serum gonadotrophins and oestradiol levels were consistent with ovarian failure in each case but there was a disproportionate elevation in serum follicle stimulating hormone (FSH) when compared to serum luteinizing hormone (LH) in 16. In 2 patients, the radiotherapeutic field extended downwards only as far as the sacral promontory. However, these 2 girls show similar evidence of ovarian failure to that in the other 16.


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