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dc.contributor.authorKinn, S R
dc.contributor.authorAllen, Terence D
dc.date.accessioned2011-06-21T16:36:34Z
dc.date.available2011-06-21T16:36:34Z
dc.date.issued1981
dc.identifier.citationConversion of blebs to microvilli: cell surface reorganisation after trypsin. 1981, 20 (2):168-73 Differentiationen
dc.identifier.issn0301-4681
dc.identifier.pmid7327317
dc.identifier.urihttp://hdl.handle.net/10541/134092
dc.description.abstractThe blebbed surface morphology produced by trypsinisation of Chinese hamster ovary cells is subsequently reorganized to a microvillous topography, even in the continued presence of trypsin. Scanning and transmission electron microscope (SEM and TEM) observations of this transition showed the initial formation of a "crown' of densely clustered microvilli at one pole of the cell. At the periphery of this region the blebs coalesced to form ridges which subsequently extended over the entire cell surface. Long, and occasionally branched microvilli were generated from the ridges. Large numbers of membrane associated vesicles were also characteristic of these areas of surface reorganisation.
dc.language.isoenen
dc.subject.meshAnimals
dc.subject.meshCell Line
dc.subject.meshCell Membrane
dc.subject.meshCricetinae
dc.subject.meshCricetulus
dc.subject.meshFemale
dc.subject.meshMicroscopy, Electron
dc.subject.meshMicroscopy, Electron, Scanning
dc.subject.meshMicrovilli
dc.subject.meshOvary
dc.subject.meshTrypsin
dc.titleConversion of blebs to microvilli: cell surface reorganisation after trypsin.en
dc.typeArticleen
dc.identifier.journalDifferentiationen
html.description.abstractThe blebbed surface morphology produced by trypsinisation of Chinese hamster ovary cells is subsequently reorganized to a microvillous topography, even in the continued presence of trypsin. Scanning and transmission electron microscope (SEM and TEM) observations of this transition showed the initial formation of a "crown' of densely clustered microvilli at one pole of the cell. At the periphery of this region the blebs coalesced to form ridges which subsequently extended over the entire cell surface. Long, and occasionally branched microvilli were generated from the ridges. Large numbers of membrane associated vesicles were also characteristic of these areas of surface reorganisation.


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