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dc.contributor.authorWright, Eric G
dc.contributor.authorAli, A M
dc.contributor.authorRiches, A C
dc.contributor.authorLord, Brian I
dc.date.accessioned2011-06-16T21:57:56Z
dc.date.available2011-06-16T21:57:56Z
dc.date.issued1982
dc.identifier.citationStimulation of haemopoietic stem cell proliferation: characteristics of the stimulator-producing cells. 1982, 6 (4):531-9 Leuk. Res.en
dc.identifier.issn0145-2126
dc.identifier.pmid7144230
dc.identifier.doi10.1016/0145-2126(82)90010-8
dc.identifier.urihttp://hdl.handle.net/10541/133540
dc.description.abstractMedia conditioned by regenerating murine bone marrow cells contain a stimulator of haemopoietic stem cell proliferation. Fractionated cell populations have been examined for production of this stimulatory activity in order to characterize its cellular source. The stimulator is produced by adherent, phagocytic, radioresistant, Thy 1.2-, Fc+ cells in a population concentrated in a density range of 1.064-1.072 g/ml. The results indicate that the producer cells reside in the heterogenous mononuclear phagocytic population of the bone marrow.
dc.language.isoenen
dc.subject.meshAnimals
dc.subject.meshBone Marrow
dc.subject.meshCell Division
dc.subject.meshCell Separation
dc.subject.meshCulture Media
dc.subject.meshGrowth Inhibitors
dc.subject.meshGrowth Substances
dc.subject.meshHematopoietic Stem Cells
dc.subject.meshMacrophages
dc.subject.meshMice
dc.subject.meshRegeneration
dc.titleStimulation of haemopoietic stem cell proliferation: characteristics of the stimulator-producing cells.en
dc.typeArticleen
dc.contributor.departmentDepartment of Anatomy and Experimental Pathology, University of St.Andrews. Fife KY16 9TSen
dc.identifier.journalLeukemia Researchen
html.description.abstractMedia conditioned by regenerating murine bone marrow cells contain a stimulator of haemopoietic stem cell proliferation. Fractionated cell populations have been examined for production of this stimulatory activity in order to characterize its cellular source. The stimulator is produced by adherent, phagocytic, radioresistant, Thy 1.2-, Fc+ cells in a population concentrated in a density range of 1.064-1.072 g/ml. The results indicate that the producer cells reside in the heterogenous mononuclear phagocytic population of the bone marrow.


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