Show simple item record

dc.contributor.authorKumar, S*
dc.contributor.authorCostello, C B*
dc.contributor.authorGlashan, R W*
dc.contributor.authorBjörklund, B*
dc.date.accessioned2011-06-16T20:42:22Z
dc.date.available2011-06-16T20:42:22Z
dc.date.issued1981-12
dc.identifier.citationThe clinical significance of tissue polypeptide antigen (TPA) in the urine of bladder cancer patients. 1981, 53 (6):578-81 Br J Urolen
dc.identifier.issn0007-1331
dc.identifier.pmid7317745
dc.identifier.doi10.1111/j.1464-410X.1981.tb03264.x
dc.identifier.urihttp://hdl.handle.net/10541/133531
dc.description.abstractA 2-stage study has been carried out to evaluate the usefulness of urinary tissue polypeptide antigen (TPA) levels in patients with bladder cancer as an adjunct to the routine procedures for detection of bladder tumours. Two-hour urine samples were collected from 83 bladder cancer patients and normal individuals for the first part of the study, 24-h samples from 54 patients and normal individuals for the second part. Urinary TPA was determined using radioimmunoassay. In 2-h samples there was no significant difference in the amounts of TPA/l in any of the groups. In contrast, the TPA results of 24-h urine samples (n = 54) were markedly different from 2-h samples and the former correlated very well with the presence or absence of bladder cancer. A reason for this difference may be circadian rhythm effects.
dc.language.isoenen
dc.subject.meshAntigens, Neoplasm
dc.subject.meshHumans
dc.subject.meshPeptides
dc.subject.meshRadioimmunoassay
dc.subject.meshTissue Polypeptide Antigen
dc.subject.meshUrinary Bladder Neoplasms
dc.titleThe clinical significance of tissue polypeptide antigen (TPA) in the urine of bladder cancer patients.en
dc.typeArticleen
dc.contributor.departmentPaediatric Oncology Laboratory, Christie Hospital, Manchesteren
dc.identifier.journalBritish Journal of Urologyen
html.description.abstractA 2-stage study has been carried out to evaluate the usefulness of urinary tissue polypeptide antigen (TPA) levels in patients with bladder cancer as an adjunct to the routine procedures for detection of bladder tumours. Two-hour urine samples were collected from 83 bladder cancer patients and normal individuals for the first part of the study, 24-h samples from 54 patients and normal individuals for the second part. Urinary TPA was determined using radioimmunoassay. In 2-h samples there was no significant difference in the amounts of TPA/l in any of the groups. In contrast, the TPA results of 24-h urine samples (n = 54) were markedly different from 2-h samples and the former correlated very well with the presence or absence of bladder cancer. A reason for this difference may be circadian rhythm effects.


This item appears in the following Collection(s)

Show simple item record