Childhood leukaemia in North West England 1954-1977: epidemiology, incidence and survival.
AffiliationChildren's Tumour Registry, Department of Epidemiology and Social Research, Christie Hospital and Holt Radium Institute, University of Manchester
MetadataShow full item record
AbstractThe annual incidence of leukaemia among children aged up to 14 years as estimated by the Manchester Children's Tumour Registry has been analysed for the 24 years 1954-1977. A significant increase in acute lymphoid leukaemia (ALL) was found, while the incidence of acute myeloid leukaemia (AML) remained constant. Other types of leukaemia were too rare to be analysed separately. The increase in ALL was concentrated among boys in the 1--5-year age group. Analysis with respect to initial white-cell count showed the increase to be more pronounced in children with initial white cell counts of 1-5 x 10(4)/microliters. The proportion of cases presenting in Lancashire compared with Greater Manchester did not change during the study period. The distribution of cases with respect to social class and socio-economic group of the parents also remained constant. Due to advances in the treatment of childhood ALL survival improved considerably during the study period and no increase in mortality was seen.
CitationChildhood leukaemia in North West England 1954-1977: epidemiology, incidence and survival. 1981, 43 (3):324-9 Br. J. Cancer
JournalBritish Journal of Cancer
- Incidence of childhood leukaemia in The Netherlands (1973-1980).
- Authors: van Steensel-Moll HA, Valkenburg HA, van Zanen GE
- Issue date: 1983 Apr
- Incidence of malignant disease in childhood: a 24-year review of the Manchester Children's Tumour Registry data.
- Authors: Birch JM, Marsden HB, Swindell R
- Issue date: 1980 Aug
- Trends in childhood leukaemia in Britain 1968-1978.
- Authors: Stiller CA, Draper GJ
- Issue date: 1982 Apr
- Incidence of childhood leukemia in Sweden 1975-1980.
- Authors: Gustafsson G, Kreuger A
- Issue date: 1982 Nov