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dc.contributor.authorLythgoe, J Pen
dc.contributor.authorPalmer, Michael Ken
dc.date.accessioned2011-05-31T15:15:18Z
dc.date.available2011-05-31T15:15:18Z
dc.date.issued1982-12
dc.identifier.citationManchester regional breast study - 5 and 10 year results. 1982, 69 (12):693-6 Br J Surgen
dc.identifier.issn0007-1323
dc.identifier.pmid7171967
dc.identifier.doi10.1002/bjs.1800691202
dc.identifier.urihttp://hdl.handle.net/10541/132414
dc.description.abstractPatients with early breast cancer (n = 1022) were treated between March 1970 and October 1975 in a prospective clinical trial. The results are presented after follow-up of 5-10 years. Clinical stage I cancer cases (n = 714) were randomly allocated to treatment by simple mastectomy and postoperative radiotherapy, or simple mastectomy alone. There was no statistically significant difference in overall survival between the two groups. There was a significant reduction in the frequency of local recurrence in those who received early postoperative radiotherapy compared with those who did not. Clinical stage II cancer cases (n = 308) were randomly allocated to treatment by simple mastectomy and postoperative radiotherapy or radical mastectomy alone. There was no statistically significant difference in survival or in the frequency of local recurrence between the two groups.
dc.language.isoenen
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBreast Neoplasms
dc.subject.meshEngland
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshHumans
dc.subject.meshMastectomy
dc.subject.meshMiddle Aged
dc.subject.meshNeoplasm Recurrence, Local
dc.subject.meshNeoplasm Staging
dc.subject.meshPostoperative Care
dc.subject.meshProspective Studies
dc.titleManchester regional breast study - 5 and 10 year results.en
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Royal Preston Hospitalen
dc.identifier.journalBritish Journal of Surgeryen
html.description.abstractPatients with early breast cancer (n = 1022) were treated between March 1970 and October 1975 in a prospective clinical trial. The results are presented after follow-up of 5-10 years. Clinical stage I cancer cases (n = 714) were randomly allocated to treatment by simple mastectomy and postoperative radiotherapy, or simple mastectomy alone. There was no statistically significant difference in overall survival between the two groups. There was a significant reduction in the frequency of local recurrence in those who received early postoperative radiotherapy compared with those who did not. Clinical stage II cancer cases (n = 308) were randomly allocated to treatment by simple mastectomy and postoperative radiotherapy or radical mastectomy alone. There was no statistically significant difference in survival or in the frequency of local recurrence between the two groups.


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