AffiliationDepartment of Histopathology, Withington Hospital and Christie Hospital, Manchester
MetadataShow full item record
AbstractTwo spindle cell carcinomas of the skin and one of the breast have been studied by electron microscopy. In one tumour the spindle cells were of purely mesenchymal type and in the other two the spindle cells exhibited both mesenchymal and epithelial features within the same cells. The significance of the findings in relation to the histogenesis of the spindle cells is discussed, with special reference to the possible alternative roles of mesenchymal metaplasia of the epithelial component and spontaneous cell fusion between carcinoma cells and stromal cells.
CitationSpindle cell squamous carcinoma: ultrastructural observations. 1982, 6 (2):197-210 Histopathology
- Spindle cell neoplasms coexpressing cytokeratin and vimentin (metaplastic squamous cell carcinoma).
- Authors: Smith KJ, Skelton HG 3rd, Morgan AM, Barrett TL, Lupton GP
- Issue date: 1992 Aug
- Spindle cell carcinoma of the breast. A clinocopathologic and ultrastructural study.
- Authors: Gersell DJ, Katzenstein AL
- Issue date: 1981 Jun
- Spindle-cell carcinoma of the upper aerodigestive tract mucosa. An immunohistologic and ultrastructural study of 18 biphasic tumors and comparison with seven monophasic spindle-cell tumors.
- Authors: Zarbo RJ, Crissman JD, Venkat H, Weiss MA
- Issue date: 1986 Nov
- Squamous metaplasia of the breast. An ultrastructural and immunologic evaluation.
- Authors: Reddick RL, Jennette JC, Askin FB
- Issue date: 1985 Oct
- [Electron microscopic and histochemical aspects of the histogenesis and diagnosis of undifferentiated squamous cell carcinoma of the skin].
- Authors: Korkmazov BM
- Issue date: 1986