Expression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines.
| dc.contributor.author | Garland, John M | |
| dc.contributor.author | Lanotte, Michael | |
| dc.contributor.author | Dexter, T Michael | |
| dc.date.accessioned | 2011-04-17T09:36:10Z | |
| dc.date.available | 2011-04-17T09:36:10Z | |
| dc.date.issued | 1982-04 | |
| dc.identifier.citation | Expression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines. 1982, 12 (4):332-6 Eur J Immunol | en |
| dc.identifier.issn | 0014-2980 | |
| dc.identifier.pmid | 6980122 | |
| dc.identifier.doi | 10.1002/eji.1830120414 | |
| dc.identifier.uri | http://hdl.handle.net/10541/128211 | |
| dc.description.abstract | Expression of 20 alpha-hydroxysteroid dehydrogenase (20 alpha-SDH), a putative T cell marker, has been examined in a number of nonlymphoid hemopoietic cell lines. Both promyelocytic and stromal bone marrow lines expressed significant 20 alpha-SDH activity which was not correlated with virus infection or growth rate. 20 alpha-SDH therefore is not a unique marker for T cells in hemopoietic tissues. This result is discussed in relationship to the action of the newly proposed interleukin 3. | |
| dc.language.iso | en | en |
| dc.subject | Haematopoietic Stem Cells | en |
| dc.subject | Acute Myeloid Leukemia | en |
| dc.subject.mesh | 20-Hydroxysteroid Dehydrogenases | |
| dc.subject.mesh | Animals | |
| dc.subject.mesh | Bone Marrow | |
| dc.subject.mesh | Cell Line | |
| dc.subject.mesh | Hematopoietic Stem Cells | |
| dc.subject.mesh | Leukemia, Myeloid, Acute | |
| dc.subject.mesh | Mice | |
| dc.subject.mesh | Mice, Inbred BALB C | |
| dc.subject.mesh | Mice, Inbred C57BL | |
| dc.subject.mesh | Mice, Inbred DBA | |
| dc.subject.mesh | T-Lymphocytes | |
| dc.title | Expression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines. | en |
| dc.type | Article | en |
| dc.contributor.department | Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester, M20 9BX, United Kingdom | en |
| dc.identifier.journal | European Journal of Immunology | en |
| html.description.abstract | Expression of 20 alpha-hydroxysteroid dehydrogenase (20 alpha-SDH), a putative T cell marker, has been examined in a number of nonlymphoid hemopoietic cell lines. Both promyelocytic and stromal bone marrow lines expressed significant 20 alpha-SDH activity which was not correlated with virus infection or growth rate. 20 alpha-SDH therefore is not a unique marker for T cells in hemopoietic tissues. This result is discussed in relationship to the action of the newly proposed interleukin 3. |