Show simple item record

dc.contributor.authorGarland, John Men
dc.contributor.authorLanotte, Michaelen
dc.contributor.authorDexter, T Michaelen
dc.date.accessioned2011-04-17T09:36:10Z
dc.date.available2011-04-17T09:36:10Z
dc.date.issued1982-04
dc.identifier.citationExpression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines. 1982, 12 (4):332-6 Eur J Immunolen
dc.identifier.issn0014-2980
dc.identifier.pmid6980122
dc.identifier.doi10.1002/eji.1830120414
dc.identifier.urihttp://hdl.handle.net/10541/128211
dc.description.abstractExpression of 20 alpha-hydroxysteroid dehydrogenase (20 alpha-SDH), a putative T cell marker, has been examined in a number of nonlymphoid hemopoietic cell lines. Both promyelocytic and stromal bone marrow lines expressed significant 20 alpha-SDH activity which was not correlated with virus infection or growth rate. 20 alpha-SDH therefore is not a unique marker for T cells in hemopoietic tissues. This result is discussed in relationship to the action of the newly proposed interleukin 3.
dc.language.isoenen
dc.subjectHaematopoietic Stem Cellsen
dc.subjectAcute Myeloid Leukemiaen
dc.subject.mesh20-Hydroxysteroid Dehydrogenases
dc.subject.meshAnimals
dc.subject.meshBone Marrow
dc.subject.meshCell Line
dc.subject.meshHematopoietic Stem Cells
dc.subject.meshLeukemia, Myeloid, Acute
dc.subject.meshMice
dc.subject.meshMice, Inbred BALB C
dc.subject.meshMice, Inbred C57BL
dc.subject.meshMice, Inbred DBA
dc.subject.meshT-Lymphocytes
dc.titleExpression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines.en
dc.typeArticleen
dc.contributor.departmentPaterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester, M20 9BX, United Kingdomen
dc.identifier.journalEuropean Journal of Immunologyen
html.description.abstractExpression of 20 alpha-hydroxysteroid dehydrogenase (20 alpha-SDH), a putative T cell marker, has been examined in a number of nonlymphoid hemopoietic cell lines. Both promyelocytic and stromal bone marrow lines expressed significant 20 alpha-SDH activity which was not correlated with virus infection or growth rate. 20 alpha-SDH therefore is not a unique marker for T cells in hemopoietic tissues. This result is discussed in relationship to the action of the newly proposed interleukin 3.


This item appears in the following Collection(s)

Show simple item record