Expression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines.
AffiliationPaterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester, M20 9BX, United Kingdom
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AbstractExpression of 20 alpha-hydroxysteroid dehydrogenase (20 alpha-SDH), a putative T cell marker, has been examined in a number of nonlymphoid hemopoietic cell lines. Both promyelocytic and stromal bone marrow lines expressed significant 20 alpha-SDH activity which was not correlated with virus infection or growth rate. 20 alpha-SDH therefore is not a unique marker for T cells in hemopoietic tissues. This result is discussed in relationship to the action of the newly proposed interleukin 3.
CitationExpression of 20 alpha-hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines. 1982, 12 (4):332-6 Eur J Immunol
JournalEuropean Journal of Immunology