Affiliation
Paterson Laboratories, Christie Hospital and Holt Radium Institute, Wilmslow Road, Withington, Manchester M20 9BX, UKIssue Date
1984-12-07
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Natural and synthetic antioxidants have been shown to repair tryptophan radicals produced from the one-electron oxidation of the free tryptophan amino acid. It has also been observed that both tryptophan and tyrosine radicals in lysozyme can be repaired by these antioxidants to varying degrees of efficiency. Although SDS-solubilized alpha-tocopherol efficiently repairs free tryptophan radicals, it is very inefficient in repairing the amino acids in lysozyme. The rigidity and immobility of solubilized alpha-tocopherol can explain this lack of efficiency.Citation
The repair of oxidized amino acids by antioxidants. 1984, 791 (2):212-8 Biochim Biophys ActaJournal
Biochimica et Biophysica ActaDOI
10.1016/0167-4838(84)90011-6PubMed ID
6509064Type
ArticleLanguage
enISSN
0006-3002ae974a485f413a2113503eed53cd6c53
10.1016/0167-4838(84)90011-6
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