Chromosomal evidence of a common stem cell in acute lymphoblastic leukemia and chronic granulocytic leukemia.
AffiliationPaterson Laboratories and Radiotherapy Department, CHristie Hospital and Holt Radium Institute, Manchester M20 9BX
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AbstractA patient with acute lymphoblastic leukemia (ALL) was found, at the time of diagnosis, to have an unusual Philadelphia chromosome (Ph1) with a satellite marker. The disease evolved into the chronic phase of chronic granulocytic leukemia (CGL), with persistance of the marker. Two months later, the patient died of ALL.
CitationChromosomal evidence of a common stem cell in acute lymphoblastic leukemia and chronic granulocytic leukemia. 1984, 13 (4):331-6 Cancer Genet. Cytogenet.
JournalCancer Genetics and Cytogenetics