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    Cutaneous vasculitis and immune complexes in severe bronchiectasis.

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    Authors
    Hilton, A M
    Hasleton, Philip S
    Bradlow, A
    Leahy, B C
    Cooper, K Michael
    Moore, M
    Affiliation
    Departments of Chest Medicine and Pathology, Wythenshawe Hospital
    Issue Date
    1984-03
    
    Metadata
    Show full item record
    Abstract
    Four patients with severe bronchiectasis (chronic bronchial suppuration) are described who developed cutaneous lesions associated with exacerbations of their respiratory disease. The skin abnormalities consisted of purpuric lesions in three patients and an erythematous vasculitis in one. Circulating immune complexes were present in all patients and in three skin biopsy specimens showed deposition of C3, IgG, and IgA in dermal blood vessels. Haemophilus influenzae had been isolated from the sputum of all four patients and in two patients was present at the time the cutaneous lesions appeared. It is suggested that local immune complex deposition was responsible for the skin lesions which occurred during acute exacerbations of bronchiectasis.
    Citation
    Cutaneous vasculitis and immune complexes in severe bronchiectasis. 1984, 39 (3):185-91 Thorax
    Journal
    Thorax
    URI
    http://hdl.handle.net/10541/124397
    DOI
    10.1136/thx.39.3.185
    PubMed ID
    6710426
    Type
    Article
    Language
    en
    ISSN
    0040-6376
    EISSN
    1468-3296
    ae974a485f413a2113503eed53cd6c53
    10.1136/thx.39.3.185
    Scopus Count
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    All Paterson Institute for Cancer Research

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