Cutaneous vasculitis and immune complexes in severe bronchiectasis.
Affiliation
Departments of Chest Medicine and Pathology, Wythenshawe HospitalIssue Date
1984-03
Metadata
Show full item recordAbstract
Four patients with severe bronchiectasis (chronic bronchial suppuration) are described who developed cutaneous lesions associated with exacerbations of their respiratory disease. The skin abnormalities consisted of purpuric lesions in three patients and an erythematous vasculitis in one. Circulating immune complexes were present in all patients and in three skin biopsy specimens showed deposition of C3, IgG, and IgA in dermal blood vessels. Haemophilus influenzae had been isolated from the sputum of all four patients and in two patients was present at the time the cutaneous lesions appeared. It is suggested that local immune complex deposition was responsible for the skin lesions which occurred during acute exacerbations of bronchiectasis.Citation
Cutaneous vasculitis and immune complexes in severe bronchiectasis. 1984, 39 (3):185-91 ThoraxJournal
ThoraxDOI
10.1136/thx.39.3.185PubMed ID
6710426Type
ArticleLanguage
enISSN
0040-6376EISSN
1468-3296ae974a485f413a2113503eed53cd6c53
10.1136/thx.39.3.185