The value of serial bone scanning in operable breast cancer.
dc.contributor.author | Monypenny, I J | |
dc.contributor.author | Grieve, R J | |
dc.contributor.author | Howell, Anthony | |
dc.contributor.author | Morrison, J M | |
dc.date.accessioned | 2011-03-12T23:31:14Z | |
dc.date.available | 2011-03-12T23:31:14Z | |
dc.date.issued | 1984-06 | |
dc.identifier.citation | The value of serial bone scanning in operable breast cancer. 1984, 71 (6):466-8 Br J Surg | en |
dc.identifier.issn | 0007-1323 | |
dc.identifier.pmid | 6722488 | |
dc.identifier.doi | 10.1002/bjs.1800710622 | |
dc.identifier.uri | http://hdl.handle.net/10541/124390 | |
dc.description.abstract | The value of initial and serial isotope bone scans was assessed in 685 patients with operable primary breast cancer. Nineteen (2.8 per cent) patients had a positive initial scan and negative skeletal radiographs; only nine of these developed other evidence of metastatic disease after a mean follow up of 21 months. Five hundred and ten patients had serial scans up to five years after simple mastectomy; 51 (10 per cent) had scan conversion, of whom 37 developed clinical or radiological confirmation of recurrent disease at a mean follow-up of 13 months. Compared with clinical or radiological methods for the detection of first metastases serial bone scans gave a mean lead time of five months in 15 patients and no lead time in the remaining 22 patients. Twelve of forty-five patients with radiologically proven bone metastases had negative scans. Neither initial or serial bone scanning is clinically useful or economically viable as a routine screening or follow-up procedure for patients with operable breast cancer. | |
dc.language.iso | en | en |
dc.subject.mesh | Adult | |
dc.subject.mesh | Axilla | |
dc.subject.mesh | Bone Neoplasms | |
dc.subject.mesh | Bone and Bones | |
dc.subject.mesh | Breast Neoplasms | |
dc.subject.mesh | Female | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Lymphatic Metastasis | |
dc.subject.mesh | Mastectomy | |
dc.subject.mesh | Middle Aged | |
dc.title | The value of serial bone scanning in operable breast cancer. | en |
dc.type | Article | en |
dc.identifier.eissn | 1365-2168 | |
dc.contributor.department | The Department of Oncology, Christie Hospital, Manchester, U.K. | en |
dc.identifier.journal | The British Journal of Surgery | en |
html.description.abstract | The value of initial and serial isotope bone scans was assessed in 685 patients with operable primary breast cancer. Nineteen (2.8 per cent) patients had a positive initial scan and negative skeletal radiographs; only nine of these developed other evidence of metastatic disease after a mean follow up of 21 months. Five hundred and ten patients had serial scans up to five years after simple mastectomy; 51 (10 per cent) had scan conversion, of whom 37 developed clinical or radiological confirmation of recurrent disease at a mean follow-up of 13 months. Compared with clinical or radiological methods for the detection of first metastases serial bone scans gave a mean lead time of five months in 15 patients and no lead time in the remaining 22 patients. Twelve of forty-five patients with radiologically proven bone metastases had negative scans. Neither initial or serial bone scanning is clinically useful or economically viable as a routine screening or follow-up procedure for patients with operable breast cancer. |