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dc.contributor.authorMonypenny, I J
dc.contributor.authorGrieve, R J
dc.contributor.authorHowell, Anthony
dc.contributor.authorMorrison, J M
dc.date.accessioned2011-03-12T23:31:14Z
dc.date.available2011-03-12T23:31:14Z
dc.date.issued1984-06
dc.identifier.citationThe value of serial bone scanning in operable breast cancer. 1984, 71 (6):466-8 Br J Surgen
dc.identifier.issn0007-1323
dc.identifier.pmid6722488
dc.identifier.doi10.1002/bjs.1800710622
dc.identifier.urihttp://hdl.handle.net/10541/124390
dc.description.abstractThe value of initial and serial isotope bone scans was assessed in 685 patients with operable primary breast cancer. Nineteen (2.8 per cent) patients had a positive initial scan and negative skeletal radiographs; only nine of these developed other evidence of metastatic disease after a mean follow up of 21 months. Five hundred and ten patients had serial scans up to five years after simple mastectomy; 51 (10 per cent) had scan conversion, of whom 37 developed clinical or radiological confirmation of recurrent disease at a mean follow-up of 13 months. Compared with clinical or radiological methods for the detection of first metastases serial bone scans gave a mean lead time of five months in 15 patients and no lead time in the remaining 22 patients. Twelve of forty-five patients with radiologically proven bone metastases had negative scans. Neither initial or serial bone scanning is clinically useful or economically viable as a routine screening or follow-up procedure for patients with operable breast cancer.
dc.language.isoenen
dc.subject.meshAdult
dc.subject.meshAxilla
dc.subject.meshBone Neoplasms
dc.subject.meshBone and Bones
dc.subject.meshBreast Neoplasms
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLymphatic Metastasis
dc.subject.meshMastectomy
dc.subject.meshMiddle Aged
dc.titleThe value of serial bone scanning in operable breast cancer.en
dc.typeArticleen
dc.identifier.eissn1365-2168
dc.contributor.departmentThe Department of Oncology, Christie Hospital, Manchester, U.K.en
dc.identifier.journalThe British Journal of Surgeryen
html.description.abstractThe value of initial and serial isotope bone scans was assessed in 685 patients with operable primary breast cancer. Nineteen (2.8 per cent) patients had a positive initial scan and negative skeletal radiographs; only nine of these developed other evidence of metastatic disease after a mean follow up of 21 months. Five hundred and ten patients had serial scans up to five years after simple mastectomy; 51 (10 per cent) had scan conversion, of whom 37 developed clinical or radiological confirmation of recurrent disease at a mean follow-up of 13 months. Compared with clinical or radiological methods for the detection of first metastases serial bone scans gave a mean lead time of five months in 15 patients and no lead time in the remaining 22 patients. Twelve of forty-five patients with radiologically proven bone metastases had negative scans. Neither initial or serial bone scanning is clinically useful or economically viable as a routine screening or follow-up procedure for patients with operable breast cancer.


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