Enhanced K-cell activity in the peripheral blood of patients with malignant disease.
dc.contributor.author | Bakács, T | |
dc.contributor.author | Czanik, P | |
dc.contributor.author | Kimber, I | |
dc.contributor.author | Ringwald, G | |
dc.contributor.author | Moore, Michael | |
dc.contributor.author | Abrahám, E | |
dc.date.accessioned | 2011-03-06T22:37:10Z | |
dc.date.available | 2011-03-06T22:37:10Z | |
dc.date.issued | 1984 | |
dc.identifier.citation | Enhanced K-cell activity in the peripheral blood of patients with malignant disease. 1984, 16 (3):170-4 Cancer Immunol. Immunother. | en |
dc.identifier.issn | 0340-7004 | |
dc.identifier.pmid | 6561069 | |
dc.identifier.doi | 10.1007/BF00205424 | |
dc.identifier.uri | http://hdl.handle.net/10541/123670 | |
dc.description.abstract | We have analysed the influence of human malignant, inflammatory and infectious disease on the capacity of peripheral lymphocytes to mediate antibody-dependent haemolysis. The application of an enzyme-like kinetic model for measurement of maximal cytotoxic function has permitted reproducible and sensitive determinations of the K-cell function. The results show that malignant disease is associated with enhancement of ADCC capacity. | |
dc.language.iso | en | en |
dc.subject.mesh | Antibody-Dependent Cell Cytotoxicity | |
dc.subject.mesh | Female | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Killer Cells, Natural | |
dc.subject.mesh | Male | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Neoplasms | |
dc.subject.mesh | Sex Factors | |
dc.title | Enhanced K-cell activity in the peripheral blood of patients with malignant disease. | en |
dc.type | Article | en |
dc.contributor.department | National Institute of Oncology, Budapest X11., Rath Gy.u.7-9, Hungary | en |
dc.identifier.journal | Cancer Immunology Immunotherapy | en |
html.description.abstract | We have analysed the influence of human malignant, inflammatory and infectious disease on the capacity of peripheral lymphocytes to mediate antibody-dependent haemolysis. The application of an enzyme-like kinetic model for measurement of maximal cytotoxic function has permitted reproducible and sensitive determinations of the K-cell function. The results show that malignant disease is associated with enhancement of ADCC capacity. |