No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study.
West, Catharine M L
Elliott, Rebecca M
AffiliationDepartment of Oncology, University of Cambridge, Cambridge, UK. firstname.lastname@example.org
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AbstractSeveral small studies have reported associations between TGFB1 single nucleotide polymorphisms (SNPs), considered to increase secretion of TGF-β1, and greater than 3-fold increases in incidence of fibrosis - an indicator of late toxicity after radiotherapy in breast cancer patients.
CitationNo association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study. 2010, 97 (1):9-14 Radiother Oncol
JournalRadiotherapy and Oncology
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