No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study.
Authors
Barnett, GColes, C
Burnet, N
Pharoah, P
Wilkinson, J
West, Catharine M L
Elliott, Rebecca M
Baynes, C
Dunning, A
Affiliation
Department of Oncology, University of Cambridge, Cambridge, UK. gillbarnett@doctors.org.ukIssue Date
2010-10
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Show full item recordAbstract
Several small studies have reported associations between TGFB1 single nucleotide polymorphisms (SNPs), considered to increase secretion of TGF-β1, and greater than 3-fold increases in incidence of fibrosis - an indicator of late toxicity after radiotherapy in breast cancer patients.Citation
No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study. 2010, 97 (1):9-14 Radiother OncolJournal
Radiotherapy and OncologyDOI
10.1016/j.radonc.2009.12.006PubMed ID
20096948Type
ArticleLanguage
enISSN
1879-0887ae974a485f413a2113503eed53cd6c53
10.1016/j.radonc.2009.12.006
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