The reversion phenomenon in irradiated fern prothalli: effects of acute or chronic anoxia and LET.
Affiliation
Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester M20 9BX, United KingdomIssue Date
1985
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In several systems a paradoxical reduction of radiation damage with increasing dose, termed reversion, has been observed. In the fern Osmunda regalis the percentage of cells which does not die but stays alive, although reproductively sterile, increases with dose. The assumed mechanism of this effect is a continuation of cytoplasmic growth during radiation-induced mitotic delay which induces terminal differentiation (early differentiation) thus preventing mitosis and the expression of chromosomal injury. Suppression of cytoplasmic growth after irradiation should abrogate reversion. This was tested using anoxia. Reversion was suppressed by storage of the sporelings in nitrogen for 8 h or more after X-rays, but was not suppressed by storage in 0.27 microM oxygen nor by a 60-min exposure to air after irradiation and before storage in nitrogen. Anoxia before irradiation in air had no effect. Anoxia only during irradiation showed an OER of about 2 for the reversion peak. The partial abrogation of reversion is consistent with the assumed mechanism. Marked reversion also was observed after 14.7 MeV neutrons.Citation
The reversion phenomenon in irradiated fern prothalli: effects of acute or chronic anoxia and LET. 1985, 24 (1):45-56 Radiat Environ BiophysJournal
Radiation and Environmental BiophysicsDOI
10.1007/BF01212652PubMed ID
3975349Type
ArticleLanguage
enISSN
0301-634Xae974a485f413a2113503eed53cd6c53
10.1007/BF01212652
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