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    The structural basis for C-banding. A scanning electron microscopy study.

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    Authors
    Jack, Elspeth M
    Harrison, Christine J
    Allen, Terence D
    Harris, R
    Affiliation
    Department of Ultrastructure and Department of Cell Biology, Paterson Laboratories, Christie Hospital & Holt Radium Institute, Manchester M20 9BX, UK
    Issue Date
    1985
    
    Metadata
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    Abstract
    The same C-banded human polymorphic chromosomes were observed in the light microscope (LM) and then in the scanning electron microscope (SEM) to investigate the structural changes produced by the C-banding technique. C-banded regions, which stained positively in LM, were highly condensed with tightly packed chromatin fibres, resembling non-banded chromosomes. In striking contrast, adjacent non-C-banded regions were represented by loosely arranged fibres, resembling G-banded chromosomes. The significance of these observations in relation to current theories on the effects of C-banding on chromosome structure is discussed.
    Citation
    The structural basis for C-banding. A scanning electron microscopy study. 1985, 91 (5):363-8 Chromosoma
    Journal
    Chromosoma
    URI
    http://hdl.handle.net/10541/117339
    DOI
    10.1007/BF00291009
    PubMed ID
    3996103
    Type
    Article
    Language
    en
    ISSN
    0009-5915
    ae974a485f413a2113503eed53cd6c53
    10.1007/BF00291009
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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