Show simple item record

dc.contributor.authorButler, John
dc.contributor.authorHoey, Brigid M
dc.contributor.authorSwallow, A John
dc.date.accessioned2010-12-07T17:14:20Z
dc.date.available2010-12-07T17:14:20Z
dc.date.issued1985-03-11
dc.identifier.citationReactions of the semiquinone free radicals of anti-tumour agents with oxygen and iron complexes. 1985, 182 (1):95-8 FEBS Letten
dc.identifier.issn0014-5793
dc.identifier.pmid3918891
dc.identifier.doi10.1016/0014-5793(85)81161-3
dc.identifier.urihttp://hdl.handle.net/10541/117337
dc.description.abstractThe rates of reaction of the semiquinone radicals of adriamycin and mitomycin C with oxygen and several iron (III) complexes have been determined. These rates have been used to explain enhanced free radical damage produced by semiquinone radicals in a model system and to assess the feasibility of these types of reactions occurring in hypoxic cells.
dc.language.isoenen
dc.subject.meshBenzoquinones
dc.subject.meshChemical Phenomena
dc.subject.meshChemistry
dc.subject.meshDoxorubicin
dc.subject.meshFerric Compounds
dc.subject.meshIron
dc.subject.meshMitomycin
dc.subject.meshMitomycins
dc.subject.meshOxygen
dc.subject.meshQuinones
dc.titleReactions of the semiquinone free radicals of anti-tumour agents with oxygen and iron complexes.en
dc.typeArticleen
dc.contributor.departmentPaterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester M20 9BX, Englanden
dc.identifier.journalFEBS Lettersen
html.description.abstractThe rates of reaction of the semiquinone radicals of adriamycin and mitomycin C with oxygen and several iron (III) complexes have been determined. These rates have been used to explain enhanced free radical damage produced by semiquinone radicals in a model system and to assess the feasibility of these types of reactions occurring in hypoxic cells.


Files in this item

This item appears in the following Collection(s)

Show simple item record