Reactions of the semiquinone free radicals of anti-tumour agents with oxygen and iron complexes.
Affiliation
Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester M20 9BX, EnglandIssue Date
1985-03-11
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The rates of reaction of the semiquinone radicals of adriamycin and mitomycin C with oxygen and several iron (III) complexes have been determined. These rates have been used to explain enhanced free radical damage produced by semiquinone radicals in a model system and to assess the feasibility of these types of reactions occurring in hypoxic cells.Citation
Reactions of the semiquinone free radicals of anti-tumour agents with oxygen and iron complexes. 1985, 182 (1):95-8 FEBS LettJournal
FEBS LettersDOI
10.1016/0014-5793(85)81161-3PubMed ID
3918891Type
ArticleLanguage
enISSN
0014-5793ae974a485f413a2113503eed53cd6c53
10.1016/0014-5793(85)81161-3
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