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    Reactions of the semiquinone free radicals of anti-tumour agents with oxygen and iron complexes.

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    Authors
    Butler, John
    Hoey, Brigid M
    Swallow, A John
    Affiliation
    Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester M20 9BX, England
    Issue Date
    1985-03-11
    
    Metadata
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    Abstract
    The rates of reaction of the semiquinone radicals of adriamycin and mitomycin C with oxygen and several iron (III) complexes have been determined. These rates have been used to explain enhanced free radical damage produced by semiquinone radicals in a model system and to assess the feasibility of these types of reactions occurring in hypoxic cells.
    Citation
    Reactions of the semiquinone free radicals of anti-tumour agents with oxygen and iron complexes. 1985, 182 (1):95-8 FEBS Lett
    Journal
    FEBS Letters
    URI
    http://hdl.handle.net/10541/117337
    DOI
    10.1016/0014-5793(85)81161-3
    PubMed ID
    3918891
    Type
    Article
    Language
    en
    ISSN
    0014-5793
    ae974a485f413a2113503eed53cd6c53
    10.1016/0014-5793(85)81161-3
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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