Mesoblastic nephroma contains fibronectin but lacks laminin.
| dc.contributor.author | Kumar, Shant | |
| dc.contributor.author | Marsden, Henry B | |
| dc.contributor.author | Carr, T | |
| dc.contributor.author | Kodet, R | |
| dc.date.accessioned | 2010-12-03T10:19:58Z | |
| dc.date.available | 2010-12-03T10:19:58Z | |
| dc.date.issued | 1985-05 | |
| dc.identifier.citation | Mesoblastic nephroma contains fibronectin but lacks laminin. 1985, 38 (5):507-11 J Clin Pathol | en |
| dc.identifier.issn | 0021-9746 | |
| dc.identifier.pmid | 2987312 | |
| dc.identifier.doi | 10.1136/jcp.38.5.507 | |
| dc.identifier.uri | http://hdl.handle.net/10541/117086 | |
| dc.description.abstract | Non-metastatic mesoblastic nephromas from four young children were shown to contain fibronectin but not laminin using an immunoperoxidase staining procedure. In contrast, one metastasising spindle celled sarcomatous tumour from a neonate was laminin positive. During embryogenesis primitive nephrogenic mesenchyme contains only fibronectin and no laminin; metanephric blastema (permanent kidney) is positive for laminin. The staining for fibronectin and laminin may help to ascertain the histogenesis of different types of renal tumour. | |
| dc.language.iso | en | en |
| dc.subject | Kidney Cancer | en |
| dc.subject | Wilms Tumour | en |
| dc.subject.mesh | Female | |
| dc.subject.mesh | Fibronectins | |
| dc.subject.mesh | Humans | |
| dc.subject.mesh | Immunoenzyme Techniques | |
| dc.subject.mesh | Infant | |
| dc.subject.mesh | Kidney Neoplasms | |
| dc.subject.mesh | Laminin | |
| dc.subject.mesh | Male | |
| dc.subject.mesh | Sarcoma | |
| dc.subject.mesh | Wilms Tumor | |
| dc.title | Mesoblastic nephroma contains fibronectin but lacks laminin. | en |
| dc.type | Article | en |
| dc.contributor.department | Christie Hospital, Manchester | en |
| dc.identifier.journal | Journal of Clinical Pathology | en |
| html.description.abstract | Non-metastatic mesoblastic nephromas from four young children were shown to contain fibronectin but not laminin using an immunoperoxidase staining procedure. In contrast, one metastasising spindle celled sarcomatous tumour from a neonate was laminin positive. During embryogenesis primitive nephrogenic mesenchyme contains only fibronectin and no laminin; metanephric blastema (permanent kidney) is positive for laminin. The staining for fibronectin and laminin may help to ascertain the histogenesis of different types of renal tumour. |