Cyclical eosinophilia: a manifestation of periodic haemopoiesis?
| dc.contributor.author | Davies, J | |
| dc.contributor.author | Geary, C | |
| dc.contributor.author | Testa, Nydia G | |
| dc.contributor.author | Pumphrey, R | |
| dc.date.accessioned | 2010-12-03T10:57:31Z | |
| dc.date.available | 2010-12-03T10:57:31Z | |
| dc.date.issued | 1985-09 | |
| dc.identifier.citation | Cyclical eosinophilia: a manifestation of periodic haemopoiesis? 1985, 61 (1):65-70 Br J Haematol | en |
| dc.identifier.issn | 0007-1048 | |
| dc.identifier.pmid | 4052333 | |
| dc.identifier.doi | 10.1111/j.1365-2141.1985.tb04061.x | |
| dc.identifier.uri | http://hdl.handle.net/10541/117077 | |
| dc.description.abstract | A patient is described who has had a marked eosinophilia of unknown cause for 9 years in association with episodic facial swelling. Weekly blood counts for 8 months showed cyclical variations in eosinophils, neutrophils and monocytes (mean cycle length 35 d). Marrow culture studies showed fluctuation in the incidence of granulocyte-macrophage colonies (GM-CFC), and the proportion of eosinophil colonies was higher than the values reported for normals. The blood lymphocyte T4/T8 ratio was reversed, due to an increase of T8+ cells. It is suggested that this condition is a rare form of periodic haemopoiesis. | |
| dc.language.iso | en | en |
| dc.subject.mesh | Aged | |
| dc.subject.mesh | Agranulocytosis | |
| dc.subject.mesh | Bone Marrow | |
| dc.subject.mesh | Colony-Forming Units Assay | |
| dc.subject.mesh | Eosinophilia | |
| dc.subject.mesh | Humans | |
| dc.subject.mesh | Leukocyte Count | |
| dc.subject.mesh | Lymphocytes | |
| dc.subject.mesh | Male | |
| dc.subject.mesh | Neutropenia | |
| dc.subject.mesh | Periodicity | |
| dc.title | Cyclical eosinophilia: a manifestation of periodic haemopoiesis? | en |
| dc.type | Article | en |
| dc.identifier.journal | British Journal of Haematology | en |
| html.description.abstract | A patient is described who has had a marked eosinophilia of unknown cause for 9 years in association with episodic facial swelling. Weekly blood counts for 8 months showed cyclical variations in eosinophils, neutrophils and monocytes (mean cycle length 35 d). Marrow culture studies showed fluctuation in the incidence of granulocyte-macrophage colonies (GM-CFC), and the proportion of eosinophil colonies was higher than the values reported for normals. The blood lymphocyte T4/T8 ratio was reversed, due to an increase of T8+ cells. It is suggested that this condition is a rare form of periodic haemopoiesis. |