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dc.contributor.authorSmith, David B
dc.contributor.authorHowell, Anthony
dc.contributor.authorHarris, Martin
dc.contributor.authorBramwell, Vivien H C
dc.contributor.authorSellwood, R A
dc.date.accessioned2010-12-02T15:13:23Z
dc.date.available2010-12-02T15:13:23Z
dc.date.issued1985-03
dc.identifier.citationCarcinomatous meningitis associated with infiltrating lobular carcinoma of the breast. 1985, 11 (1):33-6 Eur J Surg Oncolen
dc.identifier.issn0748-7983
dc.identifier.pmid2985453
dc.identifier.urihttp://hdl.handle.net/10541/116962
dc.description.abstractThe records of 365 patients with advanced carcinoma of the breast were examined to identify those with CNS involvement. Nineteen (5.2%) developed parenchymal cerebral deposits and 10 (2.7%) developed meningeal infiltration during the course of their disease. Parenchymal cerebral deposits were almost exclusively associated with infiltrating duct carcinoma (95%) and meningeal infiltration (carcinomatous meningitis) was almost exclusively associated with infiltrating lobular carcinoma. Meningeal infiltration occurred late in the course of advanced disease and was associated with diffuse involvement of the bone marrow and abdominal structures.
dc.language.isoenen
dc.subjectBrain Canceren
dc.subjectBreast Canceren
dc.subjectMeningeal Canceren
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBrain Neoplasms
dc.subject.meshBreast Neoplasms
dc.subject.meshCarcinoma
dc.subject.meshCarcinoma, Intraductal, Noninfiltrating
dc.subject.meshCombined Modality Therapy
dc.subject.meshDexamethasone
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMeningeal Neoplasms
dc.subject.meshMiddle Aged
dc.titleCarcinomatous meningitis associated with infiltrating lobular carcinoma of the breast.en
dc.typeArticleen
dc.contributor.departmentCancer Research Campaign Department of Medical Oncology, University of Manchester, Christie Hospital and Holt Radium Institute, Manchester M20 9BXen
dc.identifier.journalEuropean Journal of Surgical Oncologyen
html.description.abstractThe records of 365 patients with advanced carcinoma of the breast were examined to identify those with CNS involvement. Nineteen (5.2%) developed parenchymal cerebral deposits and 10 (2.7%) developed meningeal infiltration during the course of their disease. Parenchymal cerebral deposits were almost exclusively associated with infiltrating duct carcinoma (95%) and meningeal infiltration (carcinomatous meningitis) was almost exclusively associated with infiltrating lobular carcinoma. Meningeal infiltration occurred late in the course of advanced disease and was associated with diffuse involvement of the bone marrow and abdominal structures.


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