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dc.contributor.authorMcWilliam, L
dc.contributor.authorHarris, Martin
dc.date.accessioned2010-12-02T11:59:30Z
dc.date.available2010-12-02T11:59:30Z
dc.date.issued1985-11
dc.identifier.citationGranular cell angiosarcoma of the skin: histology, electron microscopy and immunohistochemistry of a newly recognized tumor. 1985, 9 (11):1205-16 Histopathologyen
dc.identifier.issn0309-0167
dc.identifier.pmid4085984
dc.identifier.doi10.1111/j.1365-2559.1985.tb02800.x
dc.identifier.urihttp://hdl.handle.net/10541/116920
dc.description.abstractWe report a unique angiosarcoma of the skin of the face in which a large part of the tumour was of granular cell appearance. Histologically the granular cells resembled those of conventional granular cell tumours. By electron microscopy the granules were identical to those of granular cell tumours but other features were lacking. Stains for vimentin and factor VIII related antigen were positive, but for S-100 protein and CEA were negative. The occurrence of granular cell change in an angiosarcoma supports the view that granular cell tumours are histogenetically diverse.
dc.language.isoenen
dc.subjectHaemangiosarcomaen
dc.subjectSkin Canceren
dc.subject.meshAged
dc.subject.meshCytoplasmic Granules
dc.subject.meshHemangiosarcoma
dc.subject.meshHumans
dc.subject.meshImmunoassay
dc.subject.meshMale
dc.subject.meshMicrofilaments
dc.subject.meshMicroscopy, Electron
dc.subject.meshSkin Neoplasms
dc.subject.meshVacuoles
dc.titleGranular cell angiosarcoma of the skin: histology, electron microscopy and immunohistochemistry of a newly recognized tumor.en
dc.typeArticleen
dc.contributor.departmentDepartments of Pathology, Withington and Christie Hospitals, Manchesteren
dc.identifier.journalHistopathologyen
html.description.abstractWe report a unique angiosarcoma of the skin of the face in which a large part of the tumour was of granular cell appearance. Histologically the granular cells resembled those of conventional granular cell tumours. By electron microscopy the granules were identical to those of granular cell tumours but other features were lacking. Stains for vimentin and factor VIII related antigen were positive, but for S-100 protein and CEA were negative. The occurrence of granular cell change in an angiosarcoma supports the view that granular cell tumours are histogenetically diverse.


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