Rechallenging with anthracyclines and taxanes in metastatic breast cancer.
Affiliation
Cancer Research UK Laboratories, Department of Oncology, MRC Cyclotron Building, Faculty of Medicine, Imperial College London, Du Cane Road, London W12 ONN, UK. c.palmieri@imperial.ac.ukIssue Date
2010-10
Metadata
Show full item recordAbstract
Adjuvant use of anthracycline-taxane combination therapy is an accepted strategy in the management of high-risk early-stage breast cancer. However, the introduction of this regimen raises the question of how best to manage those patients who relapse following adjuvant therapy, and whether there is a role for rechallenging in the metastatic setting with the same agent, or class of agent, that has been utilized in the adjuvant setting. This Review examines the evidence for rechallenging with both anthracyclines and taxanes, and highlights the issues that need to be examined in the context of future clinical trials.Citation
Rechallenging with anthracyclines and taxanes in metastatic breast cancer. 2010, 7 (10):561-74 Nat Rev Clin OncolJournal
Nature Reviews: Clinical OncologyDOI
10.1038/nrclinonc.2010.122PubMed ID
20808300Type
ArticleLanguage
enISSN
1759-4782ae974a485f413a2113503eed53cd6c53
10.1038/nrclinonc.2010.122
Scopus Count
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