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dc.contributor.authorHartley, Ann L
dc.contributor.authorBirch, Jillian M
dc.contributor.authorMarsden, Henry B
dc.contributor.authorHarris, Martin
dc.date.accessioned2010-11-09T16:33:50Z
dc.date.available2010-11-09T16:33:50Z
dc.date.issued1986-11
dc.identifier.citationBreast cancer risk in mothers of children with osteosarcoma and chondrosarcoma. 1986, 54 (5):819-23 Br J Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid3467784
dc.identifier.urihttp://hdl.handle.net/10541/115179
dc.description.abstractMothers of a population-based series of 86 children with osteosarcoma or chondrosarcoma were traced and their health status or cause of death ascertained. There were 6 cases of breast cancer among these mothers and 6 other cancers. Risk of breast cancer was approximately three times that expected, and appeared to be highest in mothers of boys and in mothers of children under the median age at diagnosis. The mothers who developed breast cancer were relatively young at diagnosis compared with population data. Risk of other malignancies in the mothers was not in excess of expectation. These findings are in line with those reported for breast cancer risk in mothers of children with soft tissue sarcomas, and provide further indications of a genetic component in the aetiology of these cancers.
dc.language.isoenen
dc.subjectBone Canceren
dc.subjectBreast Canceren
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshBone Neoplasms
dc.subject.meshBreast Neoplasms
dc.subject.meshChild
dc.subject.meshChondrosarcoma
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshOsteosarcoma
dc.subject.meshRisk
dc.titleBreast cancer risk in mothers of children with osteosarcoma and chondrosarcoma.en
dc.typeArticleen
dc.identifier.eissn1532-1827
dc.contributor.departmentDepartment of Epidemiology and Social Oncology, Children's Tumour Registryen
dc.identifier.journalBritish Journal of Canceren
html.description.abstractMothers of a population-based series of 86 children with osteosarcoma or chondrosarcoma were traced and their health status or cause of death ascertained. There were 6 cases of breast cancer among these mothers and 6 other cancers. Risk of breast cancer was approximately three times that expected, and appeared to be highest in mothers of boys and in mothers of children under the median age at diagnosis. The mothers who developed breast cancer were relatively young at diagnosis compared with population data. Risk of other malignancies in the mothers was not in excess of expectation. These findings are in line with those reported for breast cancer risk in mothers of children with soft tissue sarcomas, and provide further indications of a genetic component in the aetiology of these cancers.


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