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dc.contributor.authorSattar, A
dc.contributor.authorKumar, Patricia
dc.contributor.authorKumar, Shant
dc.date.accessioned2010-11-09T16:06:25Z
dc.date.available2010-11-09T16:06:25Z
dc.date.issued1986-01
dc.identifier.citationRheumatoid- and osteo-arthritis: quantitation of ultrastructural features of capillary endothelial cells. 1986, 148 (1):45-53 J Patholen
dc.identifier.issn0022-3417
dc.identifier.pmid3944671
dc.identifier.doi10.1002/path.1711480108
dc.identifier.urihttp://hdl.handle.net/10541/115173
dc.description.abstractJoint tissues from patients with rheumatoid arthritis (3), osteoarthritis (3) and normal healthy individuals (2) were examined in the transmission electron microscope and the morphological features of capillaries within 2 mm of the synovial membrane were quantified. Weibel-Palade bodies (WPB) were significantly increased in capillary endothelial cells in rheumatoid and osteoarthritis compared with normal controls, when quantified by three different methods. WPB were positively correlated with both projections of the luminal plasmalemma and pinocytic vesicles in normal joint and some patients with rheumatoid and osteoarthritis. Pinocytic vesicles and projections were also positively correlated.
dc.language.isoenen
dc.subject.meshArthritis, Rheumatoid
dc.subject.meshCapillaries
dc.subject.meshCytoplasm
dc.subject.meshEndothelium
dc.subject.meshHumans
dc.subject.meshMicroscopy, Electron
dc.subject.meshOrganoids
dc.subject.meshOsteoarthritis
dc.subject.meshPinocytosis
dc.subject.meshSynovial Membrane
dc.titleRheumatoid- and osteo-arthritis: quantitation of ultrastructural features of capillary endothelial cells.en
dc.typeArticleen
dc.identifier.eissn1096-9896
dc.contributor.departmentChristie Hospital, Manchester, M20 9BX, U.K.en
dc.identifier.journalThe Journal of Pathologyen
html.description.abstractJoint tissues from patients with rheumatoid arthritis (3), osteoarthritis (3) and normal healthy individuals (2) were examined in the transmission electron microscope and the morphological features of capillaries within 2 mm of the synovial membrane were quantified. Weibel-Palade bodies (WPB) were significantly increased in capillary endothelial cells in rheumatoid and osteoarthritis compared with normal controls, when quantified by three different methods. WPB were positively correlated with both projections of the luminal plasmalemma and pinocytic vesicles in normal joint and some patients with rheumatoid and osteoarthritis. Pinocytic vesicles and projections were also positively correlated.


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