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Nasopharyngeal carcinoma in children.

dc.contributor.authorRoper, Henry P
dc.contributor.authorEssex-Cater, A
dc.contributor.authorMarsden, Henry B
dc.contributor.authorDixon, P F
dc.contributor.authorCampbell, Richard H A
dc.date.accessioned2010-11-09T10:42:11Z
dc.date.available2010-11-09T10:42:11Z
dc.date.issued1986
dc.identifier.citationNasopharyngeal carcinoma in children. 1986, 3 (2):143-52 Pediatr Hematol Oncolen
dc.identifier.issn0888-0018
dc.identifier.pmid3153224
dc.identifier.doi10.3109/08880018609031210
dc.identifier.urihttp://hdl.handle.net/10541/115134
dc.description.abstractThe results of treatment are reviewed in 18 cases of childhood nasopharyngeal carcinoma. Since 1976 adjuvant chemotherapy with cyclophosphamide, methotrexate, and adriamycin has been used in Manchester and Leeds. The outcome is compared in 9 patients treated with radiotherapy alone and 9 patients treated later with both radiotherapy and adjuvant chemotherapy. Relapse-free survival rates were 0% for those treated with radiotherapy alone and 78% at 13-80 months after diagnosis for those treated with both radiotherapy and chemotherapy. It is concluded that adjuvant chemotherapy improves relapse-free survival in childhood nasopharyngeal carcinoma.
dc.language.isoenen
dc.subjectAnticancerous Combined Chemotherapy Protocolsen
dc.subjectNasopharyngeal Canceren
dc.subject.meshAdolescent
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols
dc.subject.meshCarcinoma
dc.subject.meshChild
dc.subject.meshCombined Modality Therapy
dc.subject.meshCyclophosphamide
dc.subject.meshDoxorubicin
dc.subject.meshFemale
dc.subject.meshGreat Britain
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMethotrexate
dc.subject.meshNasopharyngeal Neoplasms
dc.subject.meshRetrospective Studies
dc.subject.meshSex Factors
dc.titleNasopharyngeal carcinoma in children.en
dc.typeArticleen
dc.identifier.eissn1521-0669
dc.contributor.departmentDepartment of Child Health, St. Mary's Hospital, Manchester, U.K.en
dc.identifier.journalPediatric Hematology and Oncologyen
html.description.abstractThe results of treatment are reviewed in 18 cases of childhood nasopharyngeal carcinoma. Since 1976 adjuvant chemotherapy with cyclophosphamide, methotrexate, and adriamycin has been used in Manchester and Leeds. The outcome is compared in 9 patients treated with radiotherapy alone and 9 patients treated later with both radiotherapy and adjuvant chemotherapy. Relapse-free survival rates were 0% for those treated with radiotherapy alone and 78% at 13-80 months after diagnosis for those treated with both radiotherapy and chemotherapy. It is concluded that adjuvant chemotherapy improves relapse-free survival in childhood nasopharyngeal carcinoma.


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