Stage III carcinoma of cervix. The importance of increasing age and extent of parametrial infiltration.
MetadataShow full item record
AbstractThe relative importance of a number of potential prognostic factors was analysed for a sequential group of 296 patients with stage III carcinoma of the cervix who had been treated in a mature prospective clinical trial. Using a log-rank analysis of survival curves generated by the life-table method increasing age (p = 0.05) and extent of parametrial infiltration (p = 0.001) were found to be significantly related to prognosis. These two factors were further demonstrated to be independent variables and, of the two, parametrial extension (p = 0.002) was more significant than increased age (p = 0.035). Involvement of the lower third of the vagina, the presence of bullous oedema and the histological differentiation of the disease were not prognostically significant in this study. It is suggested that tumour volume as defined by extent of parametrial infiltration is a sufficiently good prognostic factor to be incorporated into a revised staging system.
CitationStage III carcinoma of cervix. The importance of increasing age and extent of parametrial infiltration. 1986, 5 (4):271-6 Radiother Oncol
JournalRadiotherapy and Oncology
- Histopathologic prognostic factors in stage II and III squamous cell carcinoma of the uterine cervix. An evaluation of 91 patients treated primarily with radiation therapy.
- Authors: Crissman JD, Budhraja M, Aron BS, Cummings G
- Issue date: 1987
- Therapeutic outcome and prognostic factors in the radiotherapy of recurrences of cervical carcinoma following surgery.
- Authors: Hille A, Weiss E, Hess CF
- Issue date: 2003 Nov
- Tumor size, irradiation dose, and long-term outcome of carcinoma of uterine cervix.
- Authors: Perez CA, Grigsby PW, Chao KS, Mutch DG, Lockett MA
- Issue date: 1998 May 1
- Residual tumour volumes and grey zones after external beam radiotherapy (with or without chemotherapy) in cervical cancer patients. A low-field MRI study.
- Authors: Schmid MP, Mansmann B, Federico M, Dimopoulous JC, Georg P, Fidarova E, Dörr W, Pötter R
- Issue date: 2013 Mar
- Uterus necrosis after radiochemotherapy in two patients with advanced cervical cancer.
- Authors: Marnitz S, Köhler C, Füller J, Hinkelbein W, Schneider A
- Issue date: 2006 Jan