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    Stage III carcinoma of cervix. The importance of increasing age and extent of parametrial infiltration.

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    Authors
    Benstead, K
    Cowie, V
    Blair, Val
    Hunter, Robin D
    Issue Date
    1986-04
    
    Metadata
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    Abstract
    The relative importance of a number of potential prognostic factors was analysed for a sequential group of 296 patients with stage III carcinoma of the cervix who had been treated in a mature prospective clinical trial. Using a log-rank analysis of survival curves generated by the life-table method increasing age (p = 0.05) and extent of parametrial infiltration (p = 0.001) were found to be significantly related to prognosis. These two factors were further demonstrated to be independent variables and, of the two, parametrial extension (p = 0.002) was more significant than increased age (p = 0.035). Involvement of the lower third of the vagina, the presence of bullous oedema and the histological differentiation of the disease were not prognostically significant in this study. It is suggested that tumour volume as defined by extent of parametrial infiltration is a sufficiently good prognostic factor to be incorporated into a revised staging system.
    Citation
    Stage III carcinoma of cervix. The importance of increasing age and extent of parametrial infiltration. 1986, 5 (4):271-6 Radiother Oncol
    Journal
    Radiotherapy and Oncology
    URI
    http://hdl.handle.net/10541/115092
    DOI
    10.1016/S0167-8140(86)80175-X
    PubMed ID
    3726165
    Type
    Article
    Language
    en
    ISSN
    0167-8140
    EISSN
    1879-0887
    ae974a485f413a2113503eed53cd6c53
    10.1016/S0167-8140(86)80175-X
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