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dc.contributor.authorRead, G
dc.contributor.authorJohnson, R J
dc.contributor.authorWilkinson, Peter M
dc.date.accessioned2010-11-08T15:38:22Z
dc.date.available2010-11-08T15:38:22Z
dc.date.issued1986-05
dc.identifier.citationThe role of radiotherapy after chemotherapy in the management of persistent para-aortic nodal disease in non-seminomatous germ cell tumours. 1986, 53 (5):623-8 Br J Canceren
dc.identifier.issn0007-0920
dc.identifier.pmid3718820
dc.identifier.urihttp://hdl.handle.net/10541/115012
dc.description.abstractIn the years 1979-1982, 83 patients with malignant teratoma of the testis who had retroperitoneal adenopathy at presentation or after a period of surveillance were treated. Complete radiological resolution of disease was obtained in 34 patients and a residual mass remained in 26, the remainder having progression of the para-aortic or other metastatic disease. There was no para-aortic relapse in 47 patients receiving radiotherapy post-chemotherapy whereas 2/11 who did not receive radiotherapy or an immediate retroperitoneal node dissection relapsed. Morbidity from radiotherapy was minimal apart from subcutaneous fibrosis in the irradiated area of 6 patients. It is concluded that radiotherapy is effective in sterilising minimal residual tumour post-chemotherapy and may be considered as an alternative to surgery.
dc.language.isoenen
dc.subjectAnticancerous Combined Chemotherapyen
dc.subjectRetroperitoneal Canceren
dc.subjectTesticular Canceren
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols
dc.subject.meshCombined Modality Therapy
dc.subject.meshHumans
dc.subject.meshLymphatic Metastasis
dc.subject.meshMale
dc.subject.meshRadiotherapy
dc.subject.meshRetroperitoneal Neoplasms
dc.subject.meshTeratoma
dc.subject.meshTesticular Neoplasms
dc.titleThe role of radiotherapy after chemotherapy in the management of persistent para-aortic nodal disease in non-seminomatous germ cell tumours.en
dc.typeArticleen
dc.identifier.journalBritish Journal of Canceren
html.description.abstractIn the years 1979-1982, 83 patients with malignant teratoma of the testis who had retroperitoneal adenopathy at presentation or after a period of surveillance were treated. Complete radiological resolution of disease was obtained in 34 patients and a residual mass remained in 26, the remainder having progression of the para-aortic or other metastatic disease. There was no para-aortic relapse in 47 patients receiving radiotherapy post-chemotherapy whereas 2/11 who did not receive radiotherapy or an immediate retroperitoneal node dissection relapsed. Morbidity from radiotherapy was minimal apart from subcutaneous fibrosis in the irradiated area of 6 patients. It is concluded that radiotherapy is effective in sterilising minimal residual tumour post-chemotherapy and may be considered as an alternative to surgery.


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