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Epstein-Barr virus (EBV) genotypes among human immunodeficiency virus (HIV)-related B-cell lymphomas and B-cell post-transplant lymphoproliferative disorders (B-PTLD)--late-onset lymphomas, especially in the HIV setting, are associated with type-B-EBV.

dc.contributor.authorIbrahim, H
dc.contributor.authorMenasce, Lia P
dc.contributor.authorPomplun, S
dc.contributor.authorBurke, M
dc.contributor.authorBower, M
dc.contributor.authorNaresh, K
dc.date.accessioned2010-10-29T15:06:17Z
dc.date.available2010-10-29T15:06:17Z
dc.date.issued2010-09
dc.identifier.citationEpstein-Barr virus (EBV) genotypes among human immunodeficiency virus (HIV)-related B-cell lymphomas and B-cell post-transplant lymphoproliferative disorders (B-PTLD)--late-onset lymphomas, especially in the HIV setting, are associated with type-B-EBV. 2010, 85 (3):227-30 Eur. J Haematolen
dc.identifier.issn1600-0609
dc.identifier.pmid20408873
dc.identifier.doi10.1111/j.1600-0609.2010.01460.x
dc.identifier.urihttp://hdl.handle.net/10541/114138
dc.description.abstractWe investigated 26 B-cell post-transplant lymphoproliferative disorders (B-PTLD) and 15 human immunodeficiency virus-related aggressive B-cell lymphomas (HIV-BCL) from England that were associated with Epstein-Barr virus (EBV) for the polymorphic sequences of the EBV-encoded nuclear antigen 3C (EBNA3C) gene to distinguish the two different EBV strains. Type-A-EBV was identified in 92% of B-PTLDS and in 53% of HIV-BCL (P = 0.003). Among HIV-BCL, patients associated with type-B-EBV had been HIV positive for significantly longer when compared to those associated with type-A (P = 0.037) although there were no correlations with ethnicity, CD4 cell counts or plasma HIV viral load.
dc.language.isoenen
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshFemale
dc.subject.meshGenotype
dc.subject.meshHIV
dc.subject.meshHerpesvirus 4, Human
dc.subject.meshHumans
dc.subject.meshLymphoma, B-Cell
dc.subject.meshLymphoproliferative Disorders
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshOrgan Transplantation
dc.subject.meshYoung Adult
dc.titleEpstein-Barr virus (EBV) genotypes among human immunodeficiency virus (HIV)-related B-cell lymphomas and B-cell post-transplant lymphoproliferative disorders (B-PTLD)--late-onset lymphomas, especially in the HIV setting, are associated with type-B-EBV.en
dc.typeArticleen
dc.contributor.departmentDepartments of Histopathology, Hammersmith Hospital and Imperial College, London, London, UK.en
dc.identifier.journalEuropean Journal of Haematologyen
html.description.abstractWe investigated 26 B-cell post-transplant lymphoproliferative disorders (B-PTLD) and 15 human immunodeficiency virus-related aggressive B-cell lymphomas (HIV-BCL) from England that were associated with Epstein-Barr virus (EBV) for the polymorphic sequences of the EBV-encoded nuclear antigen 3C (EBNA3C) gene to distinguish the two different EBV strains. Type-A-EBV was identified in 92% of B-PTLDS and in 53% of HIV-BCL (P = 0.003). Among HIV-BCL, patients associated with type-B-EBV had been HIV positive for significantly longer when compared to those associated with type-A (P = 0.037) although there were no correlations with ethnicity, CD4 cell counts or plasma HIV viral load.


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