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dc.contributor.authorZarod, A P
dc.contributor.authorRutherford, J D
dc.contributor.authorCorbitt, G
dc.date.accessioned2010-10-25T13:08:16Z
dc.date.available2010-10-25T13:08:16Z
dc.date.issued1988-03
dc.identifier.citationMalignant progression of laryngeal papilloma associated with human papilloma virus type 6 (HPV-6) DNA. 1988, 41 (3):280-3 J. Clin. Pathol.en
dc.identifier.issn0021-9746
dc.identifier.pmid2834418
dc.identifier.doi10.1136/jcp.41.3.280
dc.identifier.urihttp://hdl.handle.net/10541/113749
dc.description.abstractA case of laryngeal squamous papilloma in the early stages of development showed histological features suggestive of virus infection. Five years later positive evidence of HPV-6 infection was obtained at a time when the lesion had developed into a squamous cell carcinoma. It is concluded that this case represents a complete example of the virus to papilloma to carcinoma sequence, and as far as is known, is the first reported case of its kind in the larynx.
dc.language.isoenen
dc.subjectLaryngeal Canceren
dc.subjectTumour Virus Infectionsen
dc.subjectCancerous Cell Transformationen
dc.subject.meshAged
dc.subject.meshCarcinoma, Squamous Cell
dc.subject.meshCell Transformation, Neoplastic
dc.subject.meshDNA, Viral
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLaryngeal Neoplasms
dc.subject.meshPapilloma
dc.subject.meshPapillomaviridae
dc.subject.meshTumor Virus Infections
dc.titleMalignant progression of laryngeal papilloma associated with human papilloma virus type 6 (HPV-6) DNA.en
dc.typeArticleen
dc.contributor.departmentDepartment of Otolaryngology, Manchester Royal Infirmary, Christie Hospital and Holt Radium Institute.en
dc.identifier.journalJournal of Clinical Pathologyen
html.description.abstractA case of laryngeal squamous papilloma in the early stages of development showed histological features suggestive of virus infection. Five years later positive evidence of HPV-6 infection was obtained at a time when the lesion had developed into a squamous cell carcinoma. It is concluded that this case represents a complete example of the virus to papilloma to carcinoma sequence, and as far as is known, is the first reported case of its kind in the larynx.


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