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    Histopathology in the prediction of relapse of patients with stage I testicular teratoma treated by orchidectomy alone.

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    Authors
    Freedman, L
    Parkinson, M
    Jones, W
    Oliver, R
    Peckham, M
    Read, G
    Newlands, E
    Williams, C
    Issue Date
    1987-08-08
    
    Metadata
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    Abstract
    259 patients with stage I non-seminomatous germ-cell testicular teratoma who were treated by orchidectomy alone and monitored at one often centres in the United Kingdom were followed for a median of 30 months. 62 of the 70 relapses occurred in the first 18 months after orchidectomy. The 2-year relapse-free rate was 74%, falling to 68% at 4 years. Histological sections from 233 of the orchidectomy specimens were reviewed centrally. Four features independently predicted relapses: invasion of testicular veins, invasion of testicular lymphatics, absence of yolk-sac elements, and presence of undifferentiated tumour. An index, based on the number of these features observed, identified a high-risk subgroup of 55 patients who had a 42% relapse-free rate at 2 years.
    Citation
    Histopathology in the prediction of relapse of patients with stage I testicular teratoma treated by orchidectomy alone. 1987, 2 (8554):294-8 Lancet
    Journal
    Lancet
    URI
    http://hdl.handle.net/10541/113526
    DOI
    10.1016/S0140-6736(87)90889-0
    PubMed ID
    2886764
    Type
    Article
    Language
    en
    ISSN
    0140-6736
    ae974a485f413a2113503eed53cd6c53
    10.1016/S0140-6736(87)90889-0
    Scopus Count
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