Intraparenchymal myofibromatosis of the brain in an adult: report of an unusual case.
Affiliation
Institute of Pathology, Southwest Hospital, Chongqing, China.Issue Date
2010-06
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An unusual case of intraparenchymal myofibromatosis of the brain occurring in a 29-year-old woman is described. Preoperative CT and MRI examinations revealed two well-circumscribed nodular masses localized in the wall of the left lateral ventricle and right temporal lobe, respectively. Both masses were completely resected, and the patient remains disease-free 2 years post-surgery. Histopathologically, the lesions were characterized by stratification. From outer to inner, there was a reactive glial component, lamellated well-differentiated muscle-like cells, densely compact collagen fibers and cellular tumor with nodular and hemangiopericytoma-like patterns, respectively. The myofibroblastic nature of this tumor was verified by immunohistochemical staining and ultrastructural analysis. Intraparenchymal myofibromatosis may be confused with, and should be distinguished from, meningioma, myopericytoma, solitary fibrous tumor, leiomyoma and inflammatory myofibroblastic tumor for accurate diagnosis and optimal treatment.Citation
Intraparenchymal myofibromatosis of the brain in an adult: report of an unusual case. 2010, 30 (3):288-93 NeuropathologyJournal
NeuropathologyDOI
10.1111/j.1440-1789.2009.01065.xPubMed ID
19845864Type
ArticleLanguage
enISSN
1440-1789ae974a485f413a2113503eed53cd6c53
10.1111/j.1440-1789.2009.01065.x