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    Are germ cell tumors part of the Li-Fraumeni cancer family syndrome?

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    Authors
    Hartley, Ann L
    Birch, Jillian M
    Kelsey, Anna M
    Marsden, Henry B
    Harris, Martin
    Teare, Marion D
    Affiliation
    Department of Epidemiology and Social Oncology, Christie Hospital, Manchester, England.
    Issue Date
    1989-10-15
    
    Metadata
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    Abstract
    The occurrence of six cases of germ cell tumors, five testicular and one ovarian, in relatives of children with bone or soft tissue sarcomas is described. It is proposed that germ cell tumors may be an uncommon manifestation of the genetic predisposition to cancer that exists in the Li-Fraumeni cancer family syndrome.
    Citation
    Are germ cell tumors part of the Li-Fraumeni cancer family syndrome? 1989, 42 (2):221-6 Cancer Genet Cytogenet
    Journal
    Cancer Genetics and Cytogenetics
    URI
    http://hdl.handle.net/10541/111081
    DOI
    10.1016/0165-4608(89)90090-3
    PubMed ID
    2790757
    Type
    Article
    Language
    en
    ISSN
    0165-4608
    EISSN
    1873-4456
    ae974a485f413a2113503eed53cd6c53
    10.1016/0165-4608(89)90090-3
    Scopus Count
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    All Christie Publications

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    Related articles

    • The Li-Fraumeni cancer family syndrome.
    • Authors: Birch JM
    • Issue date: 1990 May
    • Dysgerminoma, gonadoblastoma, and testicular germ cell neoplasia in phenotypically female and male siblings with 46 XY genotype.
    • Authors: Kingsbury AC, Frost F, Cookson WO
    • Issue date: 1987 Jan 15
    • Occurrence of seminoma and dysgerminoma in father and daughter.
    • Authors: Yule SM, Dawes PJ, Malcolm AJ, Pearson AD
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    • Patterns of cancer in the families of children with soft tissue sarcoma.
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