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    Sarcomas in three generations of a family with neurofibromatosis.

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    Authors
    Hartley, Ann L
    Birch, Jillian M
    Kelsey, Anna M
    Harris, Martin
    Jones, P H
    Affiliation
    Department of Epidemiology and Social Oncology, Christie Hospital and Holt Radium Institute, Manchester, England.
    Issue Date
    1990-04
    
    Metadata
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    Abstract
    The development of sarcomas in three generations of a family with neurofibromatosis (NF) is described. A 7-month-old boy developed a prostatic rhabdomyosarcoma. Family history revealed that his maternal grandmother had died of a malignant peripheral nerve sheath tumor at age 37 years and had been affected with neurofibromatosis. His mother (aged 36 years) has also developed a malignant peripheral nerve sheath tumor and NF has been confirmed in both mother and son. This family illustrates a cluster of sarcomas associated with NF and shows the importance of thorough investigation of reported family illnesses.
    Citation
    Sarcomas in three generations of a family with neurofibromatosis. 1990, 45 (2):245-8 Cancer Genet Cytogenet
    Journal
    Cancer Genetics and Cytogenetics
    URI
    http://hdl.handle.net/10541/109790
    DOI
    10.1016/0165-4608(90)90089-S
    PubMed ID
    2107963
    Type
    Article
    Language
    en
    ISSN
    0165-4608
    ae974a485f413a2113503eed53cd6c53
    10.1016/0165-4608(90)90089-S
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