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    Epidemiological and familial aspects of hepatoblastoma.

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    Authors
    Hartley, Ann L
    Birch, Jillian M
    Kelsey, Anna M
    Jones, P H
    Harris, Martin
    Blair, Val
    Affiliation
    Department of Epidemiology and Social Oncology, Christie Hospital and Holt Radium Institute, Manchester, England.
    Issue Date
    1990
    
    Metadata
    Show full item record
    Abstract
    Data on the 20 cases of hepatoblastoma registered with the Manchester Children's Tumour Registry between 1954 and 1988 are presented. The cases represent about 0.6% of childhood malignancies and show a male:female ratio of 2.3:1. Age at presentation was almost always under 2 1/2 years. Cancer rates in close relatives were not significantly different from those expected. One family was confirmed as having Gardner syndrome, but the presence of other syndromes e.g., Beckwith-Wiedemann, could not be reliably detected in this retrospective series. The need to take an extensive pedigree and for clinical examination of other family members at the time of the child's diagnosis is emphasized.
    Citation
    Epidemiological and familial aspects of hepatoblastoma. 1990, 18 (2):103-9 Med. Pediatr Oncol
    Journal
    Medical and Pediatric Oncology
    URI
    http://hdl.handle.net/10541/109782
    DOI
    10.1002/mpo.2950180204
    PubMed ID
    2154662
    Type
    Article
    Language
    en
    ISSN
    0098-1532
    ae974a485f413a2113503eed53cd6c53
    10.1002/mpo.2950180204
    Scopus Count
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