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dc.contributor.authorGurney, H
dc.contributor.authorMurphy, D
dc.contributor.authorCrowther, Derek
dc.date.accessioned2010-08-17T09:41:33Z
dc.date.available2010-08-17T09:41:33Z
dc.date.issued1990-09
dc.identifier.citationThe management of primary fallopian tube carcinoma. 1990, 97 (9):822-6 Br J Obstet Gynaecolen
dc.identifier.issn0306-5456
dc.identifier.pmid2242368
dc.identifier.urihttp://hdl.handle.net/10541/109706
dc.description.abstractThe outcome of 30 patients with primary fallopian tube carcinoma is described. Treatment varied over the 22 year period of accrual and included combinations of surgery, radiotherapy and chemotherapy. There was an apparent increase in stage at treatment with time which was probably related to more precise staging at laparotomy and the greater use of computerized tomography. The median survival for all patients was 28 months and the 5-year survival was 18%. Ten patients received postoperative chemotherapy for residual disease with an overall response rate of 80% and median progression-free and overall survival times of 14 and 21 months respectively. The pattern of relapse was similar to that seen in ovarian carcinoma, with all but one patient having the pelvis or abdomen as the main site of recurrence. Primary fallopian tube carcinoma has a response to treatment and a tumour biology similar to that of ovarian carcinoma. It is recommended that the management of this uncommon malignancy should continue to be along the lines of ovarian carcinoma, with initial treatment by cytoreductive surgery followed by chemotherapy or radiotherapy for residual disease.
dc.language.isoenen
dc.subjectAnticancerous Agentsen
dc.subjectFallopian Tube Canceren
dc.subjectCancer Metastasisen
dc.subjectCancer Stagingen
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAntineoplastic Agents
dc.subject.meshCombined Modality Therapy
dc.subject.meshFallopian Tube Neoplasms
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshHysterectomy
dc.subject.meshMiddle Aged
dc.subject.meshNeoplasm Metastasis
dc.subject.meshNeoplasm Staging
dc.subject.meshOvariectomy
dc.subject.meshPostoperative Complications
dc.subject.meshSurvival Rate
dc.titleThe management of primary fallopian tube carcinoma.en
dc.typeArticleen
dc.contributor.departmentCancer Research Campaign Department of Medical Oncology, Christie Hospital and Holt Radium Institute, Withington, Manchester, UK.en
dc.identifier.journalBritish Journal of Obstetrics and Gynaecologyen
html.description.abstractThe outcome of 30 patients with primary fallopian tube carcinoma is described. Treatment varied over the 22 year period of accrual and included combinations of surgery, radiotherapy and chemotherapy. There was an apparent increase in stage at treatment with time which was probably related to more precise staging at laparotomy and the greater use of computerized tomography. The median survival for all patients was 28 months and the 5-year survival was 18%. Ten patients received postoperative chemotherapy for residual disease with an overall response rate of 80% and median progression-free and overall survival times of 14 and 21 months respectively. The pattern of relapse was similar to that seen in ovarian carcinoma, with all but one patient having the pelvis or abdomen as the main site of recurrence. Primary fallopian tube carcinoma has a response to treatment and a tumour biology similar to that of ovarian carcinoma. It is recommended that the management of this uncommon malignancy should continue to be along the lines of ovarian carcinoma, with initial treatment by cytoreductive surgery followed by chemotherapy or radiotherapy for residual disease.


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