Clinical studies of granulocyte colony stimulating factor (G-CSF).
AffiliationCancer Research Campaign Department of Medical Oncology, Christie Hospital, Withington, Manchester.
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AbstractGranulocyte colony stimulating factor (G-CSF) can safely stimulate the production of neutrophils in normal and neutropenic patients. Phase II studies have shown potential benefit when G-CSF is given after chemotherapy and bone marrow transplantation and in dose intensification studies. Studies in myelodysplasia, chronic neutropenia and AIDS all show great promise. Phase III studies are now in progress, which will help identify precisely the role of this exciting molecule.
CitationClinical studies of granulocyte colony stimulating factor (G-CSF). 1990, 9 (1):115-30 Cancer Surv.
- [GM-CSF and G-CSF: cytokines in clinical application].
- Authors: Ruef C, Coleman DL
- Issue date: 1991 Mar 23
- G-CSF and GM-CSF in clinical trials.
- Authors: Antman KH
- Issue date: 1990 Sep-Oct
- [Clinical use of granulocyte colony stimulating-factors (GM-CSF and G-CSF].
- Authors: Borota R, Borota J, Belić A, Gebauer E, Stefanović N
- Issue date: 1997 Mar-Apr
- [Biological properties and clinical application of filgrastim (G-CSF)].
- Authors: Robak T, Krykowski E
- Issue date: 1993
- [Report on the current indications for colony stimulating factors (G-CSF and GM-CSF)].
- Issue date: 1994 May 21