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dc.contributor.authorPonting, J
dc.contributor.authorHowell, Anthony
dc.contributor.authorPye, David A
dc.contributor.authorKumar, Shant
dc.date.accessioned2010-08-16T14:33:14Z
dc.date.available2010-08-16T14:33:14Z
dc.date.issued1992-12-02
dc.identifier.citationPrognostic relevance of serum hyaluronan levels in patients with breast cancer. 1992, 52 (6):873-6 Int. J. Canceren
dc.identifier.issn0020-7136
dc.identifier.pmid1459727
dc.identifier.doi10.1002/ijc.2910520607
dc.identifier.urihttp://hdl.handle.net/10541/109657
dc.description.abstractThe serum hyaluronan (HA) level of 238 women with breast cancer was measured by means of a specific radiometric assay. The results show no significant increase in serum HA when compared to levels in 120 control sera. A number of prognostic factors were evaluated including stage of disease, lymph-node involvement, tumour size, histology and presence of oestrogen and progesterone receptors in the tumour. No correlation was found with serum HA concentration and we conclude that serum HA level is of no prognostic significance in breast cancer.
dc.language.isoenen
dc.subjectBreast Canceren
dc.subjectCancer Stagingen
dc.subjectOestrogen Receptorsen
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshBreast Neoplasms
dc.subject.meshChi-Square Distribution
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshHyaluronic Acid
dc.subject.meshLife Tables
dc.subject.meshLymphatic Metastasis
dc.subject.meshMiddle Aged
dc.subject.meshNeoplasm Staging
dc.subject.meshPrognosis
dc.subject.meshReceptors, Estrogen
dc.subject.meshReceptors, Progesterone
dc.subject.meshSurvival Analysis
dc.titlePrognostic relevance of serum hyaluronan levels in patients with breast cancer.en
dc.typeArticleen
dc.contributor.departmentDepartment of Clinical Research, Christie Hospital, Manchester, UK.en
dc.identifier.journalInternational Journal of Cancer.en
html.description.abstractThe serum hyaluronan (HA) level of 238 women with breast cancer was measured by means of a specific radiometric assay. The results show no significant increase in serum HA when compared to levels in 120 control sera. A number of prognostic factors were evaluated including stage of disease, lymph-node involvement, tumour size, histology and presence of oestrogen and progesterone receptors in the tumour. No correlation was found with serum HA concentration and we conclude that serum HA level is of no prognostic significance in breast cancer.


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