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dc.contributor.authorVohra, R
dc.contributor.authorPrescott, R J
dc.contributor.authorBanerjee, Saumitra S
dc.contributor.authorWilkinson, Peter M
dc.contributor.authorSchofield, Philip F
dc.date.accessioned2010-08-16T13:37:06Z
dc.date.available2010-08-16T13:37:06Z
dc.date.issued1992-02
dc.identifier.citationManagement of neutropenic colitis. 1992, 1 (1):11-5 Surg Oncolen
dc.identifier.issn0960-7404
dc.identifier.pmid1341230
dc.identifier.doi10.1016/0960-7404(92)90051-L
dc.identifier.urihttp://hdl.handle.net/10541/109642
dc.description.abstractNeutropenic colitis is recognized as a rare complication of chemotherapy in haematological malignancies. By contrast, the complication is less well known in relationship to chemotherapy for solid malignancies. There are very few examples reported and this paper adds three further cases and reviews the literature. We emphasize that although some cases of neutropenic colitis may be managed medically, full thickness involvement of the bowel wall may lead to perforation and require surgery. The pathogenesis of this progression is discussed and it is concluded that clinical awareness is important in the diagnosis. The signs of peritonitis or septicaemia are indications for excisional surgery with the formation of a temporary ileostomy.
dc.language.isoenen
dc.subjectAdrenal Gland Canceren
dc.subjectColonic Canceren
dc.subjectEndodermal Sinus Tumouren
dc.subjectLiver Canceren
dc.subjectTesticular Canceren
dc.subject.meshAdrenal Gland Neoplasms
dc.subject.meshAdult
dc.subject.meshColitis
dc.subject.meshColonic Neoplasms
dc.subject.meshCombined Modality Therapy
dc.subject.meshEndodermal Sinus Tumor
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLiver Neoplasms
dc.subject.meshMale
dc.subject.meshMediastinal Neoplasms
dc.subject.meshMiddle Aged
dc.subject.meshNeutropenia
dc.subject.meshSeminoma
dc.subject.meshTeratoma
dc.subject.meshTesticular Neoplasms
dc.titleManagement of neutropenic colitis.en
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Christie NHS Trust, Withington, Manchester, UK.en
dc.identifier.journalSurgical Oncologyen
html.description.abstractNeutropenic colitis is recognized as a rare complication of chemotherapy in haematological malignancies. By contrast, the complication is less well known in relationship to chemotherapy for solid malignancies. There are very few examples reported and this paper adds three further cases and reviews the literature. We emphasize that although some cases of neutropenic colitis may be managed medically, full thickness involvement of the bowel wall may lead to perforation and require surgery. The pathogenesis of this progression is discussed and it is concluded that clinical awareness is important in the diagnosis. The signs of peritonitis or septicaemia are indications for excisional surgery with the formation of a temporary ileostomy.


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