Affiliation
Department of Histopathology, Christie Hospital and Holt Radium Institute, Withington, Manchester.Issue Date
1992-04
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Show full item recordAbstract
A middle aged man developed very high fever, status epilepticus, and terminal acute renal failure with myoglobinuria after surgery. A post mortem examination showed widespread muscle necrosis with hypercontraction bands. Muscle enzyme studies and electron microscopic examination disclosed central core disease, a condition closely related to malignant hyperpyrexia. This condition is a genetically inherited disorder which can be triggered by certain volatile anaesthetic agents or Suxamethonium. In this patient the condition may have been triggered by either the Isoflurane or the postoperative status epilepticus.Citation
Malignant hyperpyrexia: a rare cause of postoperative death. 1992, 45 (4):361-3 J Clin PatholJournal
Journal of Clinical PathologyDOI
10.1136/jcp.45.4.361PubMed ID
1577980Type
ArticleLanguage
enISSN
0021-9746ae974a485f413a2113503eed53cd6c53
10.1136/jcp.45.4.361
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