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dc.contributor.authorPearson, J Men
dc.contributor.authorKumar, Shanten
dc.contributor.authorButterworth, D Men
dc.contributor.authorSchofield, Philip Fen
dc.contributor.authorHaboubi, Najiben
dc.date.accessioned2010-08-11T17:34:44Z
dc.date.available2010-08-11T17:34:44Z
dc.date.issued1992
dc.identifier.citationFlow cytometric DNA characteristics of radiation colitis--a preliminary study., 12 (5):1647-9 Anticancer Resen
dc.identifier.issn0250-7005
dc.identifier.pmid1444231
dc.identifier.urihttp://hdl.handle.net/10541/109520
dc.description.abstractThe DNA status of 12 rectal biopsies, taken during the investigation of radiation proctitis, was investigated. Of these six were in the acute phase and six in the chronic phase. All of the acute biopsies had diploid DNA, despite bizarre histological epithelial cell appearances. Two of the chronic phase biopsies were to have aneuploid DNA profiles. This finding may be relevant to the increased risk of malignancy in irradiated tissues.
dc.language.isoenen
dc.subject.meshAcute Disease
dc.subject.meshBiopsy
dc.subject.meshCell Cycle
dc.subject.meshChronic Disease
dc.subject.meshColitis
dc.subject.meshDNA
dc.subject.meshFlow Cytometry
dc.subject.meshHumans
dc.subject.meshPloidies
dc.subject.meshRadiation Injuries
dc.subject.meshRadiotherapy
dc.titleFlow cytometric DNA characteristics of radiation colitis--a preliminary study.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, University Hospital of South Manchester, West Didsbury, England.en
dc.identifier.journalAnticancer Researchen
html.description.abstractThe DNA status of 12 rectal biopsies, taken during the investigation of radiation proctitis, was investigated. Of these six were in the acute phase and six in the chronic phase. All of the acute biopsies had diploid DNA, despite bizarre histological epithelial cell appearances. Two of the chronic phase biopsies were to have aneuploid DNA profiles. This finding may be relevant to the increased risk of malignancy in irradiated tissues.


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