Amplification of epidermal growth factor receptor gene in renal cell carcinoma.
Authors
El-Hariry, ImanPowles, Thomas
Lau, Mike R
Sternberg, Cora N
Ravaud, Alain
Von der Maase, Hans
Zantl, Niko
Harper, Peter
Rolland, Frédéric
Audhuy, Bruno
Barthel, Friederike
Machiels, Jean-Pascal
Patel, Pina
Kreuser, Ernst-Dietrick
Hawkins, Robert E
Affiliation
Oncology Business Unit, GlaxoSmithKline, London UB11 1BT, United Kingdom.Issue Date
2010-03
Metadata
Show full item recordAbstract
Expression of epidermal growth factor receptor (EGFR) may be of prognostic value in renal cell cancer (RCC). Gene amplification of EGFR was investigated in a cohort of 315 patients with advanced RCC from a previously reported randomised study. Using fluorescent in situ hybridisation, only 2 patients (0.6%) had gene amplification; therefore gene amplification is of no prognostic value in RCC.Citation
Amplification of epidermal growth factor receptor gene in renal cell carcinoma. 2010, 46 (5):859-62 Eur J CancerJournal
European Journal of CancerDOI
10.1016/j.ejca.2010.01.011PubMed ID
20167476Type
ArticleLanguage
enISSN
1879-0852ae974a485f413a2113503eed53cd6c53
10.1016/j.ejca.2010.01.011
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