Amplification of epidermal growth factor receptor gene in renal cell carcinoma.
Lau, Mike R
Sternberg, Cora N
Von der Maase, Hans
Hawkins, Robert E
AffiliationOncology Business Unit, GlaxoSmithKline, London UB11 1BT, United Kingdom.
MetadataShow full item record
AbstractExpression of epidermal growth factor receptor (EGFR) may be of prognostic value in renal cell cancer (RCC). Gene amplification of EGFR was investigated in a cohort of 315 patients with advanced RCC from a previously reported randomised study. Using fluorescent in situ hybridisation, only 2 patients (0.6%) had gene amplification; therefore gene amplification is of no prognostic value in RCC.
CitationAmplification of epidermal growth factor receptor gene in renal cell carcinoma. 2010, 46 (5):859-62 Eur J Cancer
JournalEuropean Journal of Cancer