• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Divergent differentiation in urothelial carcinoma and other bladder cancer subtypes with selected mimics.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Shanks, Jonathan H
    Iczkowski, Kenneth A
    Affiliation
    Department of Histopathology, The Christie NHS Foundation Trust, Manchester, UK. jonathan.shanks@christie.nhs.uk
    Issue Date
    2009-06
    
    Metadata
    Show full item record
    Abstract
    Conventional urothelial carcinoma accounts for most carcinomas of the urinary tract lining. However, neoplastic urothelium has the capacity to demonstrate enormous plasticity. A variety of unusual architectural patterns of urothelial carcinoma, such as the nested, microcystic and inverted variants, can be mistaken for reactive processes or benign tumours. Others such as the micropapillary, plasmacytoid and discohesive variants, can mimic metastatic tumour from other sites. The micropapillary variant in particular is more aggressive. In addition, urothelial carcinoma has a propensity to demonstrate divergent differentiation with glandular, squamous, small cell neuroendocrine, lymphoepithelioma-like, sarcomatoid or other elements. Pure squamous carcinoma or adenocarcinoma (the latter in particular) can be difficult to distinguish from contiguous or metastatic spread. Some variants have prognostic and potential therapeutic implications. Molecular genetic evidence has emerged recently supporting a close relationship between urothelial carcinoma and various divergent elements. Sarcomatoid carcinoma and its differential diagnosis with other spindle cell lesions of urinary tract will be covered in a separate review.
    Citation
    Divergent differentiation in urothelial carcinoma and other bladder cancer subtypes with selected mimics. 2009, 54 (7):885-900 Histopathology
    Journal
    Histopathology
    URI
    http://hdl.handle.net/10541/109240
    DOI
    10.1111/j.1365-2559.2008.03167.x
    PubMed ID
    19178589
    Type
    Article
    Language
    en
    ISSN
    1365-2559
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1365-2559.2008.03167.x
    Scopus Count
    Collections
    All Christie Publications
    Pathology

    entitlement

    Related articles

    • Recently described and unusual variants of urothelial carcinoma of the urinary bladder.
    • Authors: Samaratunga H, Delahunt B
    • Issue date: 2012 Aug
    • Carcinoma of the urinary bladder: a review of its diverse morphology.
    • Authors: Eble JN, Young RH
    • Issue date: 1997 May
    • High-grade urothelial carcinoma of the renal pelvis: clinicopathologic study of 108 cases with emphasis on unusual morphologic variants.
    • Authors: Perez-Montiel D, Wakely PE, Hes O, Michal M, Suster S
    • Issue date: 2006 Apr
    • Urothelial carcinoma with villoglandular differentiation: a study of 14 cases.
    • Authors: Lim M, Adsay NV, Grignon D, Osunkoya AO
    • Issue date: 2009 Oct
    • [Specific types of bladder cancer].
    • Authors: Bertz S, Hartmann A, Knüchel-Clarke R, Gaisa NT
    • Issue date: 2016 Feb
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.