• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Lifestyle factors and colorectal cancer risk (2): a systematic review and meta-analysis of associations with leisure-time physical activity.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Harriss, D J
    Atkinson, G
    Batterham, A
    George, K
    Cable, N Tim
    Reilly, Thomas
    Haboubi, Najib
    Renehan, Andrew G
    Affiliation
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.
    Issue Date
    2009-09
    
    Metadata
    Show full item record
    Abstract
    OBJECTIVE: Increased physical activity may decrease the risk of colorectal cancer. As a prerequisite to the determination of lifestyle attributable risks, we performed a systematic review and meta-analysis of prospective observational studies to quantify gender-specific risk associated with increased leisure-time physical activity (LT-PA). METHOD: We searched MEDLINE and EMBASE (to December 2007), and other sources, selecting reports based on strict inclusion criteria. We used random-effects meta-analyses to estimate summary risk ratios (RR) and 95% confidence intervals (95% CI) for uppermost vs lowermost categories of physical activity. To investigate dose-response, we explored risks ratios as a function of cumulative percentiles of physical activity distribution. RESULTS: Fifteen datasets from 14 articles, including 7873 incident cases, were identified. For colon cancer, there were inverse associations with LT-PA for men (RR: 0.80; 95% CI: 0.67-0.96) and women (0.86; 0.76-0.98). LT-PA did not influence risk of rectal cancer. The dose-response analysis was consistent with linear pattern reductions in risk of colon cancer in both genders. There was evidence of moderate between-study heterogeneity but summary estimates were broadly consistent across potential confounding factors. CONCLUSION: Increased LT-PA is associated with a modest reduction in colon but not rectal cancer risk; a risk reduction, which previously may have been overstated. LT-PA only interventions in public health cancer prevention strategies are unlikely to impact substantially on colorectal cancer incidences.
    Citation
    Lifestyle factors and colorectal cancer risk (2): a systematic review and meta-analysis of associations with leisure-time physical activity. 2009, 11 (7):689-701 Colorectal Dis
    Journal
    Colorectal Disease
    URI
    http://hdl.handle.net/10541/109235
    DOI
    10.1111/j.1463-1318.2009.01767.x
    PubMed ID
    19207713
    Type
    Article
    Language
    en
    ISSN
    1463-1318
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1463-1318.2009.01767.x
    Scopus Count
    Collections
    All Christie Publications
    Surgery

    entitlement

    Related articles

    • Lifestyle factors and colorectal cancer risk (1): systematic review and meta-analysis of associations with body mass index.
    • Authors: Harriss DJ, Atkinson G, George K, Cable NT, Reilly T, Haboubi N, Zwahlen M, Egger M, Renehan AG, C-CLEAR group.
    • Issue date: 2009 Jul
    • Fish consumption and colorectal cancer risk in humans: a systematic review and meta-analysis.
    • Authors: Wu S, Feng B, Li K, Zhu X, Liang S, Liu X, Han S, Wang B, Wu K, Miao D, Liang J, Fan D
    • Issue date: 2012 Jun
    • Domain-specific physical activity and sedentary behaviour in relation to colon and rectal cancer risk: a systematic review and meta-analysis.
    • Authors: Mahmood S, MacInnis RJ, English DR, Karahalios A, Lynch BM
    • Issue date: 2017 Dec 1
    • Commentary: How obesity and physical activity contribute to colorectal cancer.
    • Authors: Pisani P
    • Issue date: 2009 Sep
    • Is diabetes mellitus an independent risk factor for colon cancer and rectal cancer?
    • Authors: Yuhara H, Steinmaus C, Cohen SE, Corley DA, Tei Y, Buffler PA
    • Issue date: 2011 Nov
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.