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    Circulating tumour-derived predictive biomarkers in oncology.

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    Authors
    Hodgson, Darren R
    Wellings, Robert
    Orr, Maria C M
    McCormack, Rose
    Malone, Michael
    Board, Ruth E
    Cantarini, Mireille V
    Affiliation
    Oncology Therapy Area, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK. darren.hodgson@astrazeneca.com
    Issue Date
    2010-02
    
    Metadata
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    Abstract
    Molecular characterization of tumour material will become increasingly important in selecting patients for clinical trials and offering appropriate treatment for patients in clinical practice. Recent advances in the field have indicated that the molecular characteristics of a tumour can be determined from circulating tumour cells and circulating tumour DNA; thus, a simple blood sample could provide these data in a simple, convenient and efficient manner. This article discusses progress towards guiding treatment decisions through measuring tumour-derived factors in the circulation.
    Citation
    Circulating tumour-derived predictive biomarkers in oncology. 2010, 15 (3-4):98-101 Drug Discov Today
    Journal
    Drug Discovery Today
    URI
    http://hdl.handle.net/10541/109044
    DOI
    10.1016/j.drudis.2009.12.006
    PubMed ID
    20045486
    Type
    Article
    Language
    en
    ISSN
    1878-5832
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.drudis.2009.12.006
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