• Login
    View Item 
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    The clonogen content of murine intestinal crypts: dependence on radiation dose used in its determination.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Hendry, Jolyon H
    Roberts, Stephen A
    Potten, Christopher S
    Affiliation
    Cancer Research Campaign Department of Experimental Radiation Oncology, Paterson Institute for Cancer Research, Christie Hospital (NHS) Trust, Manchester, United Kingdom.
    Issue Date
    1992-10
    
    Metadata
    Show full item record
    Abstract
    The number of colony-forming (clonogenic) cells in each of the crypts in mouse small intestine was deduced using a two-dose irradiation technique. The number was 7.5 +/- 0.8 cells using two equal doses each less than 9 Gy and 38 +/- 7 cells using 9 Gy or more per dose. The significant dose dependence could not be accounted for by considerations of intra- or intercrypt variability, or by the factor introduced to correct the sampling frequency for the influence of crypt size. The results suggest that more colony-forming cells may be recruited when the injury is more severe.
    Citation
    The clonogen content of murine intestinal crypts: dependence on radiation dose used in its determination. 1992, 132 (1):115-9 Radiat. Res.
    Journal
    Radiation Research
    URI
    http://hdl.handle.net/10541/108928
    PubMed ID
    1410267
    Type
    Article
    Language
    en
    ISSN
    0033-7587
    Collections
    All Paterson Institute for Cancer Research

    entitlement

    Related articles

    • The effect of proliferative status and clonogen content on the response of mouse jejunal crypts to split-dose irradiation.
    • Authors: Thames HD, Ruifrok AC, Mason KA
    • Issue date: 1997 Feb
    • Deduction of the clonogen content of intestinal crypts: a direct comparison of two-dose and multiple-dose methodologies.
    • Authors: Roberts SA, Hendry JH, Potten CS
    • Issue date: 1995 Mar
    • Enhancement of murine intestinal stem cell survival after irradiation by keratinocyte growth factor.
    • Authors: Khan WB, Shui C, Ning S, Knox SJ
    • Issue date: 1997 Sep
    • [Radiobiology of stem cells in intestinal epithelium. Effect of single and multiple preliminary sublethal irradiation of mice on the dose dependence of the survival of stem cells in small intestine epithelium].
    • Authors: Konopliannikova OA
    • Issue date: 1988 Jan-Feb
    • [Individual variability in the number of stem cells in mammalian tissues].
    • Authors: Gushchin VA, Blank MA
    • Issue date: 1995
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.