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dc.contributor.authorChen, Xiaoyi
dc.contributor.authorPepper, Stuart D
dc.contributor.authorArrand, John R
dc.date.accessioned2010-08-03T10:06:25Z
dc.date.available2010-08-03T10:06:25Z
dc.date.issued1992-02
dc.identifier.citationPrevalence of the A and B types of Epstein-Barr virus DNA in nasopharyngeal carcinoma biopsies from southern China. 1992, 73 ( Pt 2):463-6 J. Gen. Virol.en
dc.identifier.issn0022-1317
dc.identifier.pmid1311369
dc.identifier.doi10.1099/0022-1317-73-2-463
dc.identifier.urihttp://hdl.handle.net/10541/108891
dc.description.abstractEpstein-Barr virus (EBV) exists in the human population in two genetic forms, usually referred to as type A and type B. Although many earlier studies had indicated that the A type was generally predominant, there were suggestions that the B type may exhibit a preferential tropism for nasopharyngeal epithelial cells. This study examines the prevalence of the two forms of EBV DNA present in nasopharyngeal carcinoma biopsies obtained from the high incidence area of Southern China. The results obtained by Southern blot or polymerase chain reaction analyses show that in this patient group the A type of EBV is predominant.
dc.language.isoenen
dc.subjectTumour Virus Infectionsen
dc.subjectNasopharyngeal Canceren
dc.subject.meshBase Sequence
dc.subject.meshBlotting, Southern
dc.subject.meshChina
dc.subject.meshDNA, Viral
dc.subject.meshElectrophoresis, Agar Gel
dc.subject.meshHerpesvirus 4, Human
dc.subject.meshHumans
dc.subject.meshMolecular Sequence Data
dc.subject.meshNasopharyngeal Neoplasms
dc.subject.meshNucleic Acid Hybridization
dc.subject.meshPolymerase Chain Reaction
dc.subject.meshPrevalence
dc.subject.meshTumor Virus Infections
dc.titlePrevalence of the A and B types of Epstein-Barr virus DNA in nasopharyngeal carcinoma biopsies from southern China.en
dc.typeArticleen
dc.contributor.departmentCancer Research Campaign Laboratories, Paterson Institute for Cancer Research, Christie CRC Cancer Centre, Manchester, U.K.en
dc.identifier.journalJournal of General Virologyen
html.description.abstractEpstein-Barr virus (EBV) exists in the human population in two genetic forms, usually referred to as type A and type B. Although many earlier studies had indicated that the A type was generally predominant, there were suggestions that the B type may exhibit a preferential tropism for nasopharyngeal epithelial cells. This study examines the prevalence of the two forms of EBV DNA present in nasopharyngeal carcinoma biopsies obtained from the high incidence area of Southern China. The results obtained by Southern blot or polymerase chain reaction analyses show that in this patient group the A type of EBV is predominant.


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