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    Erythropoietin and myeloid colony stimulating factors.

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    Authors
    Cowling, Graham J
    Dexter, T Michael
    Affiliation
    CRC Department of Experimental Haematology, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester, UK.
    Issue Date
    1992-10
    
    Metadata
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    Abstract
    The production of blood cells in the body is controlled by at least 20 polypeptide growth factors. Most of these factors have been cloned and many expressed in bacterial and eukaryotic systems to give biologically active proteins. Currently, these recombinant human proteins are undergoing intensive evaluation for their use in treating primary haemopoietic diseases, or stimulating normal haemopoiesis following drug-, radiation- or virus-induced trauma of the bone marrow. Erythropoietin (EPO) and the myeloid colony stimulating factors (IL-3, G-CSF, GM-CSF and M-CSF) were among the first to be cloned and expressed.
    Citation
    Erythropoietin and myeloid colony stimulating factors. 1992, 10 (10):349-57 Trends Biotechnol.
    Journal
    Trends in Biotechnology
    URI
    http://hdl.handle.net/10541/108875
    DOI
    10.1016/0167-7799(92)90267-Y
    PubMed ID
    1368874
    Type
    Article
    Language
    en
    ISSN
    0167-7799
    ae974a485f413a2113503eed53cd6c53
    10.1016/0167-7799(92)90267-Y
    Scopus Count
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    All Paterson Institute for Cancer Research

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