Chronic lung fibrosis following carmustine (BCNU) chemotherapy: radiological features.
AffiliationDepartment of Diagnostic Radiology, University of Manchester.
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AbstractCarmustine (BCNU) is a cytotoxic drug which is a recognized cause of acute pulmonary fibrosis. We describe the radiological findings in six patients who received carmustine in childhood for treatment of central nervous system tumours and were subsequently found to have pulmonary fibrosis 13-17 years after treatment. Patients were studied by chest radiography and high resolution computed tomography. The pattern of disease is novel, involving the upper zones in a predominantly peripheral pattern.
CitationChronic lung fibrosis following carmustine (BCNU) chemotherapy: radiological features. 1991, 44 (5):299-301 Clin Radiol
- Active lung fibrosis up to 17 years after chemotherapy with carmustine (BCNU) in childhood.
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